Results 251 to 260 of about 2,639,603 (318)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Agreement Between Intraoperative Findings and Histopathological Diagnosis and Their Association with Postoperative Outcomes in Acute Appendicitis. [PDF]

Diagnostics (Basel)
Maleš I, Šarić A, Lovrinčević I, Božić J, Pogorelić Z.   +4 more
europepmc   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Predictors of Root Resorption in Lateral Incisors Adjacent to Maxillary Impacted Canines in CBCT Images: A Retrospective Study. [PDF]

Clin Exp Dent Res
Moshfeghi M, Hosseini M, Iranparvar P, Momeni A, Eslamiamirabadi N, Biria M.   +5 more
europepmc   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Healing Beyond Words: A Randomized Controlled Trial of Sandplay and Art Therapies for PTSD Among Syrian Refugee Children in Jordan. [PDF]

Int J Pediatr
Al-Fakih A, Alzoubi A, Alrawashdeh A, Alsulaiman JW, Ba-Shammakh SA, Khasawneh A, Dannecker K, Kheirallah KA.   +7 more
europepmc   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Association Between Early Childhood Caries and Systemic Inflammatory Profiles: A Retrospective Analysis of Children Undergoing Dental Treatment Under General Anesthesia. [PDF]

Children (Basel)
Tez Yaşar BÇ, Çakmak AB, Eberliköse H, Güler AY, Kızıltan Eliaçık BB, Karasu HA.   +5 more
europepmc   +1 more source

Baricitinib for Itch-Dominant Atopic Dermatitis: A 52-week Baricitinib Real-World Experience in Korea. [PDF]

Ann Dermatol
Hong N, Gwag HE, Park SY, Heo SJ, Jung HJ, Park MY, Choi YS, Ahn J.   +7 more
europepmc   +1 more source

Analysis of factors associated with severity categories of fall-related injuries among inpatients at a tertiary grade A hospital in Zhejiang province from 2015 to 2025: a retrospective observational study. [PDF]

BMJ Open
Wang X, Sun L, Quan L, Fan M, Wang Z.
europepmc   +1 more source