Results 31 to 40 of about 59,310 (292)

Family-Based Association Analysis of Alcohol Dependence Criteria and Severity [PDF]

Alcoholism: Clinical and Experimental Research, 2013
Despite the high heritability of alcohol dependence (AD), the genes found to be associated with it account for only a small proportion of its total variability. The goal of this study was to identify and analyze phenotypes based on homogeneous classes of individuals to increase the power to detect genetic risk factors contributing to the risk of AD.The
Wetherill, Leah, Kapoor, Manav, Agrawal, Arpana, Bucholz, Kathleen, Koller, Daniel, Bertelsen, Sarah, Le, Nhung, Wang, Jen-Chyong, Almasy, Laura, Hesselbrock, Victor, Kramer, John, Nurnberger, John, Tischfield, Jay, Xuei, Xiaoling, Porjesz, Bernice, Edenberg, Howard, Goate, Alison, Foroud, Tatiana, Schuckit, Marc   +18 more
openaire   +5 more sources

The effectiveness and cost-effectiveness of a stepped care intervention for alcohol use disorders in primary care: a pilot study [PDF]

, 2009
Background Screening for alcohol use disorders identifies a wide range of needs, varying from hazardous and harmful drinking to alcohol dependence. Stepped care offers a potentially resource-efficient way of meeting these needs, but requires evaluation ...
Peters, Timothy, James, Darren, Russell, Ian, Rollnick, Stephen, Drummond, Colin, Ford, David, Drummond, Colin; id_orcid, David Ford, Baxter, John, Godfrey, Christine, Lervy, Bruce, Coulton, Simon, Parrott, Steve   +12 more
core   +1 more source

Feasibility randomized controlled trial of cognitive and behavioral interventions for depression symptoms in patients accessing drug and alcohol treatment [PDF]

, 2015
Depressed mood often co-exists with frequent drug and alcohol use. This trial examined the feasibility of screening, recruitment, randomization and engagement of drug and alcohol users in psychological interventions for depression symptoms. A total of 50
Delgadillo, J., Gilbody, Simon, Gore, Stuart, Ekers, D., Gilchrist, G., Delgadillo, Jaime, Ekers, David, Hughes, E., McMillan, D., Gilchrist, Gail; id_orcid, McMillan, Dean, Ali, Shehzad, Gilbody, S., Hughes, Elizabeth, Ali, S., Gilchrist, Gail, Gore, S.   +16 more
core   +1 more source

How CAGE, RAPS4QF and AUDIT can help practitioners for patients admitted with acute alcohol intoxication in emergency departments?

Frontiers in Psychiatry, 2014
Aims: To help clinicians to identify the severity of Alcohol Use Disorders (AUD) from optimal thresholds found for recommended scales. Especially, taking account of the high prevalence of alcohol dependence among patients admitted to the Emergency ...
Georges eBrousse, Georges eBrousse, Benjamin eArnaud, Julie eGeneste, Bruno ePereira, Ingrid eDe Chazeron, Ingrid eDe Chazeron, Frederique eTeissedre, Christophe ePerrier, Raymund eSchwan, Laurent eMalet, Jeannot eSchmidt, Pierre Michel eLlorca, Pierre Michel eLlorca, Cheryl J. Cherpitel   +14 more
doaj   +1 more source

Study of prevalence of Sexual dysfunction in Alcohol Dependant individuals: A cross sectional study [PDF]

Perspectives In Medical Research, 2017
Background: The chances of developing sexual dysfunctions appear to increase with increasing years of alcohol consumed. Various explanations have been offered for sexual dysfunction in alcoholic patients.
Pavan Kumar K1 , Apurva Chada2 , Ravinder Anaveni3 , Sinjoni Roy4
doaj  

Cognitive Dysfunctions in Patients with Alcohol Dependence Syndrome in a Tertiary Hospital in Kathmandu

Journal of Nepal Medical Association, 2016
Introduction: Alcohol dependence is a chronic disorder, accompanied by neuropsychological deficits. Patients with alcohol dependence were evaluated to identify the cognitive dysfunctions.
Sirjana Adhikari, Mita Rana, Suraj Shakya, Saroj Prasad Ojha   +3 more
doaj   +3 more sources

Study of association of erectile dysfunction in male subjects with the severity of alcohol dependence

Industrial Psychiatry Journal
Background: Alcohol dependence syndrome is a major public health problem, and it impacts the social, psychological, medical, economic, and religious spheres of our existence. Persistent alcohol abuse impacts sexual functioning negatively and leads to the
Priyank Singh Mehta, Priyadarshee Patra, Santosh Tapasi   +2 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

An Observational Study on Domestic Violence, Marital Satisfaction, and Psychiatric Morbidities in Wives of Alcohol Use Disorder Males [PDF]

Indian Journal of Private Psychiatry
Background: Alcohol is a commonly consumed substance that induces intoxication and can lead to dependence. Alcoholism is often referred to as a family disease due to its harmful impact on the lives of family members and its maximum impact is felt on ...
Roshani K Patel, Pradip N Dalsaniya, Punit Patel, Mukesh K Patel   +3 more
doaj   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source