Results 161 to 170 of about 177,712,728 (307)

Gastrointestinal Symptoms in Systemic Sclerosis: Prevalence and Severity across Disease Subtypes and Autoantibody Profiles. [PDF]

Acta Med Litu
Vujovic Sestakov M, Lukovic S, Pavlovic I, Zlatanovic M, Ostojic P.   +4 more
europepmc   +1 more source

Epidemiology of COVID-19 and the Utility of Cycle Threshold (Ct) Values in Predicting the Severity of Disease. [PDF]

Cureus, 2023
George A, Murugan T, Sampath S, N S M.
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Obstructive sleep apnea severity, Alzheimer's disease plasma markers, and CSF brain amyloidosis and tau pathology. [PDF]

Alzheimers Dement
Bubu OM, Mullins AE, Shah S, Gills JL, Kam K, Parekh A, Umasabor-Bubu OQ, Turner AD, Bernard M, Briggs A, Ramos-Cejudo J, Valkanova E, Mbah AK, Pahari P, Debure L, Ghuman M, Boutajangout A, Williams NJ, Hwang J, Williams MK, Rapoport DM, Ayappa I, de Léon M, Jean-Louis G, Varga AW, Osorio RS.   +25 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Fifth disease (slapped cheek syndrome)

, 2015
What is fifth disease Fifth disease, which is also known as ?slapped cheek syndrome? or erythema infectiosum is a common viral infection caused by parvovirus B19.
Centre for Disease Control
core  

Risk Factor Analysis Based on Disease Severity: Rosacea Disease Management Strategies and Personalized Recommendations. [PDF]

J Cosmet Dermatol
Liu H, Zhang L, Yuan J, Liang J, Zhang Y, Gao Z, Chen Y, Wang Y, Li Y, Zeng W, Yang F.   +10 more
europepmc   +1 more source

The Influence of Severity and Disease Duration on TNF Receptors' Redistribution in Asthma and Rheumatoid Arthritis. [PDF]

Cells, 2022
Alshevskaya A, Lopatnikova J, Zhukova J, Chumasova O, Shkaruba N, Sizikov A, Evsegneeva I, Demina D, Nepomniashchikch V, Karaulov A, Sennikov S.   +10 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source