Results 111 to 120 of about 465,142 (341)

ACCURACY OF THE EOSINOPHILIC ESOPHAGITIS ENDOSCOPIC REFERENCE SCORE IN CHILDREN [PDF]

Arquivos de Gastroenterologia
Background: To assess the efficacy of applying the endoscopic reference score for EoE (EREFS) in children with symptoms of esophageal dysfunction naïve to proton pump inhibitor (PPI) therapy. Methods: An observational cross-sectional study was conducted
Luciana M RIBEIRO, Mário C VIEIRA, Sabine K TRUPPEL, Nelson A ROSÁRIO FILHO   +3 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce, Goknur Selen Kocak, José Verdú‐Díaz, Jorge Alonso‐Pérez, Kristl G. Claeys, Tanya Stojkovic, Gorka Fernández‐Eulate, Pascal Laforêt, Najoua Miladi, Filipe Di Pace, Cristiane Araujo Martins Moreno, Edmar Zanoteli, Conrad C. Weihl, Volker Straub, Ana Töpf, Jordi Díaz‐Manera, Sarcoglycan European Cohort Consortium, Adele D′Amico, Adolfo López de Munain, Alicia Alonso‐Jiménez, Ana Camacho‐Salas, Andrea Gangfuß, Andrés Nascimento, Anna Sarkozy, Anneke J. van der Kooi, Arturo Fraga‐Bau, Béla Melegh, Benedikt Schoser, Bjarne Udd, Blaz Koritnik, Carlos Ortez, Chiara Marini Bettolo, Chiara Panicucci, Claudia Weiss, Claudio Bruno, Claudio Semplicini, Cristina Dominguez‐González, Cristina Garrido, David Gómez‐Andrés, Edoardo Malfatti, Elena Pegoraro, Elke De Vos, Francina Munell, Gabriele Dekomien, Giacomo Pietro Comi, Giorgio Tasca, Isabelle Richard, Jan L. De Bleecker, Jana Haberlová, Jesper Helbo Storgaard, Johanna Palmio, John Vissing, Juan Carlos de Leon‐Hernández, Kinga Hadzsiev, Laura Costa‐Comellas, Lea Leonardis, Leroy ten Dam, Lidia González‐Quereda, Luca Bello, Luisa Politano, Manuela Santos, Marianne de Visser, Marie Rohlenová, Matteo Garibaldi, Michela Guglieri, Nicolas Deconinck, Nicoline Løkken, Omar Abdel‐Mannan, Pia Gallano, Roberto Fernández‐Torrón, Ulrike Schara‐Schmidt, Vincenzo Nigro, Vittoria Zangaro   +72 more
wiley   +1 more source

The Effectiveness of CURB-65 and PSI Scores in Predicting Hospital Length of Stay in Patients Diagnosed with Community-Acquired Pneumonia in the Emergency Department

Van Tıp Dergisi
INTRODUCTION: Community-acquired pneumonia (CAP) is a major cause of infectious disease mortality and a burden on healthcare systems. CURB-65 and Pneumonia Severity Index (PSI) scores assess disease severity and guide hospitalization decisions, but their
Murtaza Kaya, Mustafa Kaan Oduncuoğlu, Harun Yıldırım, Abdil Çoşkun, Ali Halici, Yesim Tunc   +5 more
doaj   +1 more source

Performance of Brazilian Pediatric Risk of Severity Model for Illness (Brprism) Compared to Pediatric Index of Mortality and Pediatric Risk of Mortality 2

, 2023
C. M. F. Mangia, M. D. Toledo, R. Rossi, E. Y. Nakano, A. Carneluti, B. I. Kopelman, W. B. Carvalho, M. C. Andrade   +7 more
openalex   +1 more source

Heart Rate Variability Using The Analgesia Nociception Index as A Predictor of Illness Severity and Mortality in Critically Ill Patients with COVID-19. [PDF]

, 2020
Cristian Aragón‐Benedí, Pablo Oliver-Forniés, Felice Galluccio, Ece Yamak Altınpulluk, Tolga Ergönenç, Abdallah El-Sayed Allam, Carlos Salazar, Mario Fajardo‐Pérez   +7 more
openalex   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Evaluation of the effectiveness of quick COVID-19 Severity Index and COVID-GRAM Critical Illness Risk Score in determining mortality and severity in COVID-19

, 2022
Hüseyin Acar, Ahmet Kayalı, Serkan Bılgın, Adnan Yamanoğlu, Zeynep Karakaya, Fatih Esad Topal, Kadriye Acar   +6 more
openalex   +2 more sources

Variables Predicting the Severity of a Mass Shooting: the connection to white supremacy [PDF]

, 2018
Since mass shootings have become increasingly relevant in today’s society, the subject of what makes a mass shooting deadly has become more and more popular.
Resnick, Sarina
core   +1 more source

[Estimation of severity of illness in intensive care: validation of physiologic stability index].

Revista chilena de pediatria, 1991
Physiological stability index (PSI) is a score proposed to evaluate the severity of different diseases in pediatric intensive care units (PICU) by giving scores to the deterioration of 34 measurable physiological variables. In order to validate PSI, it was prospectively applied to 132 patients who entered our PICU. A significant difference (p less than
A, Caichac, P, Lorca, S, Hanning, S, Peña, M, Neilson   +4 more
openaire   +1 more source