Results 211 to 220 of about 175,590,241 (301)

Lactate Drives Pathological Browning of White Adipose Tissue to Aggravate Sepsis‐Associated Metabolic Disorders in a GPR81‐Dependent Manner

Advanced Science, EarlyView.
Sepsis‐triggered lactate accumulation induces pathological white adipose tissue browning. Lactate activates adipocyte GPR81 to sequentially upregulate CTRP6‐p38 signalling and UCP1 expression. This cascade exacerbates sepsis‐associated metabolic disorders.
Chunliang Zheng, Xiaohua Li, Shuo Li, Chungen Xing, Chun Cao   +4 more
wiley   +1 more source

Association between admission undernutrition and mortality rates and adverse outcomes in a pediatric intensive care unit in India: a prospective cohort study. [PDF]

Front Pediatr
Kalrao VR, Pramod A.
europepmc   +1 more source

ReLink: Reliable Deep Learning for Microscopic Motion Tracking

Advanced Science, EarlyView.
ReLink enables reliable trajectory linking in single‐particle tracking by integrating physics‐informed motion statistics with confidence‐based adaptive filtering. Across diverse simulated and experimental conditions, ReLink robustly reconstructs trajectories and preserves the fidelity of downstream analyses, enabling accurate characterization of ...
Yuan Jiang, Xiaochen Feng, Hongda Wei, Hao Sha, Hongpeng Wang, Min Zhang, Sanyang Han, Yongbing Zhang   +7 more
wiley   +1 more source

Distinct Health-Related Quality of Life Recovery Trajectories Among ICU Survivors: A Multicentre Prospective Cohort Study Using the EQ-5D-5L. [PDF]

Nurs Crit Care
Kang J, Jeong Y.
europepmc   +1 more source

Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

Advanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin, Jian Lyu, Yanci Liu, Zhiyuan Feng, Jie Bao, Wenxiong Song, Bingcheng Zhu, Minghao Liu, Jionghao Xue, Jiadi Weng, Jiani Zhang, Jizong Zhao, Xiaolin Chen, Bin Dong   +13 more
wiley   +1 more source

Heterogeneity of Critical Organ Dysfunction During Late-Onset Bacteremia in Preterm Infants.

JAMA Netw Open
Liu S, Missigman E, Al Gharaibeh FN, Park WY, Lawler B, Kuiper JR, Makker K, Moreira AG, Wynn JL, Aziz KB.   +9 more
europepmc   +1 more source

Dynamic monitoring of a core pro-inflammatory cytokine panel improves mortality prediction in severe influenza. [PDF]

Front Immunol
Mai K, Wang Y, Qu W, Weng Y, Lin Z, Chen L, Oliveira A, Zhong N, Hon C, Pan W, Yang Z.   +10 more
europepmc   +1 more source

Tuning Local Modulus at Liquid Metal‐Polymer Interfaces Regulates Electrocaloric Effect in Ferroelectric Nanocomposites

Advanced Electronic Materials, EarlyView.
Liquid metal nanoparticles create mechanically compliant polymer interfaces that facilitate reversible dipolar reorientation under electric fields, whereas rigid interfaces impose stronger local constraints. This soft–rigid interface comparison reveals local interfacial modulus as a key parameter for tuning electrocaloric entropy change in ...
Tian Yao, Shanyu Zheng, Binzhou Sun, Zhenhua Ma, Feiyu Zhang, Lu Yu, Qiang Li, Ruhong Luo, Feihong Du, Yifan Zhao, Yezhan Lin, Chunyu Wang, Xin Chen, Shi‐Yang Tang, Tiannan Yang, Xiaoshi Qian   +15 more
wiley   +1 more source

Integrating frailty and acute illness severity scoring for risk stratification in acute geriatric care: Review and practical guide. [PDF]

World J Crit Care Med
Khaw MJ, Chin WV.
europepmc   +1 more source

Acute illness severity index for severe cardiovascular disease patients using machine learning approaches

Communications Medicine
Hao Ren, Fengshi Jing, Hao Liu, Weitao Cai, Xu Yu, Zeyu Luo, Xingyuan Tian, Lizhi Chen, Jiandong Zhou, Yu Sun, Wen Jin, Weibin Cheng   +11 more
openaire   +1 more source