Results 131 to 140 of about 49,945 (259)
Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm
British Journal of Pharmacology, EarlyView.Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley +1 more source
Surviving Males With PORCN Variants: Expanding the Clinical, Molecular, and Mechanistic Spectrum
Clinical Genetics, EarlyView.Pathogenic PORCN variants are compatible with male survival in both mosaic and non‐mosaic states, expanding the FDH/PONGOS spectrum and improving diagnosis and genetic counseling. ABSTRACT Pathogenic variants in PORCN cause focal dermal hypoplasia (FDH/Goltz syndrome), an X‐linked dominant disorder historically considered lethal in males, with milder ...
Lucía Miranda‐Alcaraz +23 more
wiley +1 more source
Early Medieval Europe, EarlyView.This article presents a newly discovered Latin text: a theological treatise titled Liber testimoniorum veteris testamenti that was written by Alcuin’s friend Candidus (Wizo) at the request of Charlemagne. By discussing selected passages from the Heptateuch, Candidus seeks to demonstrate that Jesus Christ and the Holy Spirit, thus the whole Christian ...
Lukas J. Dorfbauer
wiley +1 more source
Exploring the leaky pipeline: Tokenism, status group effects, or self‐selection?
European Management Review, EarlyView.Abstract In most European universities today, more than 50% of bachelor's degrees are awarded to women, but the corresponding share of full professorships is only about 25%. This phenomenon is called the leaky pipeline. Most explanations refer to gender biases and stereotypes, motherhood, discrimination, and tokenism.
Margit Osterloh, Katja Rost
wiley +1 more source
History of sexually transmitted infections among mpox cases in the 2022 outbreak in Spain
HIV Medicine, EarlyView.Abstract Objective The aim was to describe the history of sexually transmitted infections (STIs) among adult mpox men cases and to analyse sociodemographic and epidemiological characteristics according to the presence or absence of any STI diagnosed 1 or 6 months previous to mpox diagnosis during the 2022 outbreak in Spain.
Aina March‐Yagüe +35 more
wiley +1 more source
Impact of climate on the migration phenology of the endangered Little Bustard in Spain
Ibis, EarlyView.The phenology of animals is closely tied to seasonal climatic patterns so, by altering temperature and precipitation regimes, climate change disrupts the phenological cycles of species. More specifically, the influence of rising temperatures on the phenology of bird migration has been long studied.
Irene Hernández‐Téllez +6 more
wiley +1 more source
Insect Conservation and Diversity, EarlyView.Here, we used a unique 37‐year (1969–2006) freshwater macroinvertebrate time‐series, collected over seven sites in central Germany, to study biodiversity patterns and species accumulation over time. Accumulation curves of Diptera diversity have not reached a plateau in 37 years of sampling.
Nathan Jay Baker +10 more
wiley +1 more source
Insect Conservation and Diversity, EarlyView.We compiled the first checklist of wild bees in Doñana Protected Area, documenting 385 species, including three vulnerable and one endangered species listed in the Red List. Bee species exhibit diverse floral preferences, highlighting the need to incorporate plant–pollinator interactions and the role of plants in conservation and management strategies ...
Francisco P. Molina +3 more
wiley +1 more source