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Biomonitoring occupational sevoflurane exposure at low levels by urinary sevoflurane and hexafluoroisopropanol

Toxicology Letters, 2014
This study aimed to correlate environmental sevoflurane levels with urinary concentrations of sevoflurane (Sev-U) or its metabolite hexafluoroisopropanol (HFIP) in order to assess and discuss the main issues relating to which biomarker of sevoflurane exposure is best, and possibly suggest the corresponding biological equivalent exposure limit values ...
Maria Luisa Scapellato   +6 more
openaire   +4 more sources

Effect of Equipotent Doses of Propofol versus Sevoflurane Anesthesia on Regulatory T Cells after Breast Cancer Surgery

Anesthesiology, 2018
What We Already Know about This Topic Cluster of differentiation enzymes on regulatory T cells are immunosuppressive and promote cancer recurrence The investigators tested the hypothesis that cluster of differentiation 39 and 73 expression is increased ...
Chung-Sik Oh   +7 more
semanticscholar   +1 more source

Sevoflurane impairs m6A-mediated mRNA translation and leads to fine motor and cognitive deficits

Cell Biology and Toxicology, 2021
Lei Zhang   +11 more
semanticscholar   +1 more source

Sevofluran: Metabolismus und Toxizität

Der Anaesthesist, 1998
The new inhalational anesthetic sevoflurane is biotransformed by approximately 5%. Serum fluoride concentrations resulting from transformation mainly depend on rate of hepatic defluorination, total amount of anesthetic given and the solubility of the volatile anesthetic, as expressed by its blood gas partition coefficient. Enflurane is metabolized by 5-
Peter Conzen, M Nuscheler, Klaus Peter
openaire   +3 more sources

Clinical Sevoflurane Metabolism and Disposition

Survey of Anesthesiology, 1995
Background Sevoflurane has low blood and tissue solubility and is metabolized to free fluoride and hexafluoroisopropanol (HFIP). Although sevoflurane uptake and distribution and fluoride formation have been described, the pharmacokinetics of HFIP formation and elimination are incompletely understood.
Michael D. Karol   +3 more
openaire   +3 more sources

Sevoflurane: Are There Differences in Products?

Anesthesia & Analgesia, 2007
Sevoflurane is currently available in the United States from two manufacturers: Ultane (Abbott Laboratories, Inc.) and a generic product, Sevoflurane Inhalation Anesthetic (Baxter Healthcare Corp.). These products are rated therapeutically equivalent by the Food and Drug Administration, but there are some differences.
openaire   +3 more sources

Metabolism of Sevoflurane

Anesthesia & Analgesia, 1991
Burnell R. Brown, Edward J. Frink
openaire   +4 more sources

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