Results 61 to 70 of about 1,896,970 (311)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
La salud: ¿una cuestión de género?
Avances en Enfermería, 1996 <p>La referencia a "género", conduce al concepto de feminidad y no de masculinidad. La relación salud género concibe programas para mujeres, niños y ancianos. Ofrece alternativas para el "hombre productor-político-guerrero" no para hombres débiles,
Velandia Mora Manuel Antonio
doaj
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Does sex education influence sexual and reproductive behaviour of women? Evidence from Mexico [PDF]
This article examines the influence of sex education on sexual and reproductive behavior in Mexican women. Exposure to in-school sex education is identified and duration-hazard models are estimated to assess its effects on initiation of sexual activity ...
Pamela Ortiz Arévalo
core
In the Shadow of a Myth: Bargaining for Same-Sex Divorce [PDF]
, 2017 This Article explores a relatively new phenomenon in family law: same-sex divorce. The Article\u27s central claim is that parties to the first wave of same-sex divorces are not effectively bargaining against the backdrop of legal dissolution rules that ...
Ben-Asher, Noa
core +2 more sources
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
A nonsmooth two-sex population model
, 2014 This paper considers a two-dimensional logistic model to study populations with two genders. The growth behavior of a population is guided by two coupled ordinary differential equations given by a non-differentiable vector field whose parameters are the ...
Garibaldi, Eduardo, Sobottka, Marcelo
core +1 more source
Sex differences in the influence of body mass index on anatomical architecture of brain networks. [PDF]
, 2017 Background/objectivesThe brain has a central role in regulating ingestive behavior in obesity. Analogous to addiction behaviors, an imbalance in the processing of rewarding and salient stimuli results in maladaptive eating behaviors that override ...
Alaverdyan, M +12 more
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Bulletin of the World Health Organization, 2001 OBJECTIVE: A cross-sectional survey was conducted in three districts of Quang Ninh province, Viet Nam, to find out what proportion of the people who lived there engaged in behaviour that put them at risk of becoming infected with HIV, and to measure ...
Bui Thang D. +6 more
doaj