Results 81 to 90 of about 1,896,970 (311)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

General population and HIV prevention: from risk to action

Cadernos de Saúde Pública
Since knowledge about AIDS transmission now appears to be very good, many observers are surprised that more people do not practice behavior, like safer sex, designed to minimize risk of contracting the disease. Still, previous studies have not shown that
Geneviève Paicheler
doaj  

“That's Where the Arguments Come in”: A Qualitative Analysis of Booster Sessions following a Brief Intervention for Drug Use and Intimate Partner Violence in the Emergency Department

Substance Abuse: Research and Treatment, 2016
Although booster phone calls have been used to enhance the impact of brief interventions in the emergency department, there has been less number of studies describing the content of these boosters.
Esther K. Choo, Chantal Tapé, Kimberly M. Glerum, Michael J. Mello, Caron Zlotnick, Kate Morrow Guthrie   +5 more
doaj   +1 more source

EFFECTS OF SEX, ENVIRONMENT, AND CONDITION ON THE MUSKING BEHAVIOR OF SYMPATRIC GARTERSNAKES (THAMNOPHIS SPP.) [PDF]

, 2014
Despite an abundance of studies documenting antipredator and defensive behaviors of gartersnakes (genus Thamnophis), few have quantitatively examined musking, a widely utilized antipredator tactic.
Bertolatus, David, Gagliardi-Seeley, Jennifer L., Gangloff, Eric, Reigel, Christopher   +3 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Mulher e anticoncepção: conhecimento e uso de métodos anticoncepcionais

Cadernos de Saúde Pública
Neste estudo buscou-se fazer uma análise do conhecimento e do uso de métodos anticoncepcionais (MAC) entre mulheres de 10 a 49 anos residentes na Região Sul do Município de São Paulo, no ano de 1992.
Néia Schor, Andrea Felicissimo Ferreira, Vera L. Machado, Ana Paula França, Kátia C. M. Pirotta, Augusta Thereza de Alvarenga, Arnaldo Augusto Franco de Siqueira   +6 more
doaj  

Sexual behavior among unmarried business process outsourcing employees in Chennai: Gender differences and correlates associated with It

Indian Journal of Public Health, 2013
Background: Premarital sex is often associated with high risk sexual behavior such as early age of initiation, multiple partners and inconsistent condom use. Evidence shows that such sexual behavior pre-disposes to sexually transmitted diseases including
Bimal Charles, Saumya Rastogi, Asirvatham Edwin Sam, Joseph D Williams, Aarthi Kandasamy   +4 more
doaj   +1 more source

Unsafe Sex, AIDS, and Development [PDF]

Much of Africa has been ravaged by the AIDS epidemic. There, heterosexual contact is the primary mode of transmission for the HIV virus. Even when access to condoms is good and their price low, a large fraction of young Africans continue to engage in ...
Bhattacharya, Joydeep, Bunzel, Helle, Qiao, Xue   +2 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source