Results 81 to 90 of about 1,890,522 (312)

Strategy selection during exploratory behavior: sex differences

Judgment and Decision Making, 2007
This study was designed to assess sex-related differences in the selection of an appropriate strategy when facing novelty. A simple visuo-spatial task was used to investigate exploratory behavior as a specific response to novelty.
Catherine Brandner
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

General population and HIV prevention: from risk to action

Cadernos de Saúde Pública
Since knowledge about AIDS transmission now appears to be very good, many observers are surprised that more people do not practice behavior, like safer sex, designed to minimize risk of contracting the disease. Still, previous studies have not shown that
Geneviève Paicheler
doaj  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Caminhoneiros de rota curta e sua vulnerabilidade ao HIV, Santos, SP

Revista de Saúde Pública
OBJETIVO: Descrever a vulnerabilidade, de caminhoneiros de rota curta, à transmissão sexual do HIV e da Aids. MÉTODOS: Foram entrevistados 279 caminhoneiros com vínculo de trabalho na cidade de Santos, SP, em locais de concentração na área portuária e ...
Luciana Villarinho, Ivanilda Bezerra, Regina Lacerda, Maria do Rosario Dias de Oliveira Latorre, Vera Paiva, Ron Stall, Norman Hearst   +6 more
doaj  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Mulher e anticoncepção: conhecimento e uso de métodos anticoncepcionais

Cadernos de Saúde Pública
Neste estudo buscou-se fazer uma análise do conhecimento e do uso de métodos anticoncepcionais (MAC) entre mulheres de 10 a 49 anos residentes na Região Sul do Município de São Paulo, no ano de 1992.
Néia Schor, Andrea Felicissimo Ferreira, Vera L. Machado, Ana Paula França, Kátia C. M. Pirotta, Augusta Thereza de Alvarenga, Arnaldo Augusto Franco de Siqueira   +6 more
doaj  

“That's Where the Arguments Come in”: A Qualitative Analysis of Booster Sessions following a Brief Intervention for Drug Use and Intimate Partner Violence in the Emergency Department

Substance Abuse: Research and Treatment, 2016
Although booster phone calls have been used to enhance the impact of brief interventions in the emergency department, there has been less number of studies describing the content of these boosters.
Esther K. Choo, Chantal Tapé, Kimberly M. Glerum, Michael J. Mello, Caron Zlotnick, Kate Morrow Guthrie   +5 more
doaj   +1 more source

Sexual behavior among unmarried business process outsourcing employees in Chennai: Gender differences and correlates associated with It

Indian Journal of Public Health, 2013
Background: Premarital sex is often associated with high risk sexual behavior such as early age of initiation, multiple partners and inconsistent condom use. Evidence shows that such sexual behavior pre-disposes to sexually transmitted diseases including
Bimal Charles, Saumya Rastogi, Asirvatham Edwin Sam, Joseph D Williams, Aarthi Kandasamy   +4 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source