Results 121 to 130 of about 3,125,192 (336)

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Difference in out-of-school physical activity patterns, sedentary behavior, and health-related fitness in relation to mathematics achievement among school-aged children: a cross-sectional study

Frontiers in Education
AimThis study examined differences in health-related fitness, physical activity patterns, and sedentary behavior among Qatari schoolchildren, classified by their mathematics achievement levels.MethodsNinety-eight schoolchildren (age: 12.1 ± 0.5 years ...
Souhail Hermassi, Wissem Dhahbi, Wissem Dhahbi, Nidhal Jebabli, Abdulla Alneama, Sascha Ketelhut, Roland van den Tillaar   +6 more
doaj   +1 more source

HLA-DRB1* genotypes in Greek rheumatoid arthritis patients: association with disease characteristics, sex and age at onset [PDF]

, 1997
C Stavropoulos, M. Spyropoulou, Y. Koumantaki, I. Kappou, P. V. Kaklamanis, Athena Linos, Ernestini Giziaki, E. Kaklamani   +7 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Prediction of Sexual Functioning and Sexual Self-Efficacy in Women Based on Signs and Symptoms of Behavioral Problems

Taḥqīqāt-i ̒Ulūm-i Raftārī, 2018
Aim and Background: Behavioral problems can affect sexual behavior. Therefore, this study aimed to predict sexual function and female sexual self-efficacy based on the components of behavioral problems.
شهرام وزیری, سهیلا کلوانی   +1 more
doaj  

CMR Left Ventricular Filling Pressure Exhibits Strong Haemodynamic Relevance and Outperforms Echocardiography in Multimodal Heart Failure Assessment

Journal of Cardiovascular Development and Disease
Background: Left ventricular filling pressure (LVFP) is pivotal in heart failure management, yet non-invasive assessment remains challenging. While echocardiography is the first line, cardiovascular magnetic resonance (CMR) offers enhanced accuracy. This
Aradhai Bana, Rui Li, Zia Mehmood, Craig Rogers, Ciaran Grafton-Clarke, Tiya Bali, David Hall, Mustapha Jamil, Liandra Ramachenderam, Uwais Dudhiya, Hilmar Spohr, Victoria Underwood, Rebekah Girling, Bahman Kasmai, Sunil Nair, David P. Ripley, Gareth Matthews, Pankaj Garg   +17 more
doaj   +1 more source

Sex determination by reference to dental plaster casts of young adults

Australasian Orthodontic Journal, 1989
Dental plaster casts of young Caucasians were examined by dentists with the objective of determining the sex of the subjects from whom they were taken. The first hypothesis tested was that dentists cannot distinguish the sexes, and second, that dentists ...
Wendei Evans R., Faulkner Keith D.B.
doaj   +1 more source

Primary sex determination in birds depends on DMRT1 dosage, but gonadal sex does not determine adult secondary sex characteristics. [PDF]

Proc Natl Acad Sci U S A, 2021
Ioannidis J, Taylor G, Zhao D, Liu L, Idoko-Akoh A, Gong D, Lovell-Badge R, Guioli S, McGrew MJ, Clinton M.   +9 more
europepmc   +1 more source

Representatives and Senators: Trends in Member Characteristics Since 1945 [PDF]

, 2012
[Excerpt] This report provides profiles of Senators and Representatives in selected Congresses since 1945. It includes data based on Representatives and Senators serving on the first day of the 79th, 82nd, 87th, 92nd, 97th, 102nd, and 107th – 112th ...
Petersen, R. Eric
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source