Results 81 to 90 of about 1,745,129 (313)

Sex-Specific Differences in Pre-Stroke Characteristics Reveal Vulnerability of Elderly Women

, 2022
While the sexually dimorphic character of ischemic stroke has been acknowledged along several dimensions, age-specific sex disparities regarding pre-stroke characteristics in particular have received comparatively little attention.
Carolin Hoyer, Anne Ebert, Kristina Szabo, Vesile Sandikci, Matthias Wittayer, Michael Platten, Jan Schlenker   +6 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Sex- and Age-Related Metabolic Characteristics of Serum Free Fatty Acids in Healthy Chinese Adults

, 2020
Free fatty acids (FFAs), also named nonesterified fatty acids, largely originate from the lipolysis of triacylglycerol stored in adipose tissue. Despite extensive research on sex- and age-dependent effects on lipolysis and lipid mobilization of adipose ...
Xiaohui Liu (6412), Fangjia Hao, Jiashuai Huang (8550567), Yuqian Bao (290496), Lixin Wang (343011), Linjing Zhao (1951681), Weiping Jia (44939), Wei Jia (136607), Xiaohui Liu, Weiping Jia, Aihua Zhao (136578), Aihua Zhao, Xiaojing Ma, Congrong Wang, Wei Jia, Yuqian Bao, Congrong Wang (44941), Jiashuai Huang, Lixin Wang, Fangjia Hao (8550564), Linjing Zhao, Xiaojing Ma (44943)   +21 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Menstrual Cycle Phase Influences Cognitive Performance in Women and Modulates Sex Differences: A Combined Longitudinal and Cross-Sectional Study

Biology
Sex hormones’ and menstrual cycle’s effects on cognitive performance remain unclear. This study examined cognitive differences between women across menstrual cycle phases, sex differences between women and men, and hormone–cognition associations.
Angelika K. Sawicka, Katarzyna M. Michalak, Barbara Naparło, Adrià Bermudo-Gallaguet, Maria Mataró, Pawel J. Winklewski, Anna B. Marcinkowska   +6 more
doaj   +1 more source

Foreign travel, casual sex, and sexually transmitted infections: systematic review and meta-analysis. [PDF]

, 2010
OBJECTIVES: With increasing international travel it is important to understand how frequent casual travel sex and unprotected intercourse are, and what impact this may have on the risk of acquiring sexually transmitted infections (STIs).
R. Vivancos, Hunter, PR, P.R. Hunter, Vivancos, R., Vivancos, R, Hunter, P.R., Abubakar, I, Abubakar, I., I. Abubakar   +8 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Anthropometric Foot Variations in Children: A Cross‐Sectional Study Supporting Sex‐Based Last Design

Journal of Foot and Ankle Research
Introduction Proper shoe fit is essential for healthy foot development in children. Despite growing interest in the ergonomics of pediatric footwear, scientific evidence on sex‐based foot morphology remains limited.
Manuel Pereira Domínguez, Sara García Blanco, Concepción Paralera‐Morales, Aranza Requena Martínez, María P. Quintana‐Montesdeoca, Aníbal Báez‐Suárez   +5 more
doaj   +1 more source

Sex Chromosomes

, 1967
Sex Chromosomes focuses on the study of sex chromosomes, including human chromosomal abnormalities, behavior and characteristics of chromosomes, and cell division.
Mittwoch, Ursula
core  

Learning Disabilities and Serious Crime – Sex Offences

, 2009
This review paper follows on from two previous reviews of the literature with regard to, firstly, learning disability and murder and, secondly, learning disability and arson.
Read, Fiona, Read, Elspeth
core   +1 more source