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Degenerated, Undifferentiated, Rearranged, Lost: High Variability of Sex Chromosomes in Geometridae (Lepidoptera) Identified by Sex Chromatin [PDF]

open access: yesCells, 2021
Sex chromatin is a conspicuous body that occurs in polyploid nuclei of most lepidopteran females and consists of numerous copies of the W sex chromosome.
Martina Hejníčková   +7 more
doaj   +2 more sources

The multicopy gene Sly represses the sex chromosomes in the male mouse germline after meiosis. [PDF]

open access: yesPLoS Biology, 2009
Studies of mice with Y chromosome long arm deficiencies suggest that the male-specific region (MSYq) encodes information required for sperm differentiation and postmeiotic sex chromatin repression (PSCR).
Julie Cocquet   +6 more
doaj   +5 more sources

Egr1 is a sex-dependent regulator of neuronal chromatin, structural plasticity, and behaviour [PDF]

open access: yesNature Communications
Sex differences are found in brain structure and function across species, and across brain disorders in humans. A major source of brain sex differences is differential secretion of steroid hormones from the gonads across the lifespan.
Devin Rocks   +8 more
doaj   +2 more sources

The epigenome of evolving Drosophila neo-sex chromosomes: dosage compensation and heterochromatin formation. [PDF]

open access: yesPLoS Biology, 2013
Sex chromosomes originated from autosomes but have evolved a highly specialized chromatin structure. Drosophila Y chromosomes are composed entirely of silent heterochromatin, while male X chromosomes have highly accessible chromatin and are ...
Qi Zhou   +5 more
doaj   +7 more sources

Intrauterine hyperglycemia impairs mouse primordial germ cell development and fertility by sex-specific epigenetic reprogramming interference [PDF]

open access: yesCell Discovery
Adverse intrauterine environments, such as hyperglycemia, impair sexual reproduction and species continuity, yet the underlying mechanisms remain poorly understood.
Jiangshan Cong   +12 more
doaj   +2 more sources

A ROLE FOR CELLULAR IMMUNITY IN EARLY POSTPARTUM PERIOD

open access: yesМедицинская иммунология, 2021
The functioning of the secretory organs is closely related to the activity of the immune system. As is well known, this participation is manifested in the fact that at certain stages of activity, the lymphoid cells migrating to the organ can be involved ...
N. A. Panova, V. G. Skopichev
doaj   +1 more source

Correlation between Sex Chromatin and Female Breast Tumour in Paraffin Sections, Buccal Smears and Peripheral Blood Films [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Introduction: Sex chromatin is a plano-convex to triangular DNA mass measuring approximately 1µm in size and lying adjacent to the inner side of nuclear membrane in the somatic cells of the females.
Bodal Vijay Kumar   +7 more
doaj   +1 more source

Plasma growth hormone pulses induce male-biased pulsatile chromatin opening and epigenetic regulation in adult mouse liver

open access: yeseLife, 2023
Sex differences in plasma growth hormone (GH) profiles, pulsatile in males and persistent in females, regulate sex differences in hepatic STAT5 activation linked to sex differences in gene expression and liver disease susceptibility, but little is ...
Andy Rampersaud   +2 more
doaj   +1 more source

A mammal-specific Doublesex homolog associates with male sex chromatin and is required for male meiosis. [PDF]

open access: yesPLoS Genetics, 2007
Gametogenesis is a sexually dimorphic process requiring profound differences in germ cell differentiation between the sexes. In mammals, the presence of heteromorphic sex chromosomes in males creates additional sex-specific challenges, including ...
Shinseog Kim   +6 more
doaj   +1 more source

H3K27ac chromatin acetylation and gene expression analysis reveal sex- and situs-related differences in developing chicken gonads

open access: yesBiology of Sex Differences, 2022
Background Birds exhibit a unique asymmetry in terms of gonad development. The female left gonad generates a functional ovary, whereas the right gonad regresses. In males, both left and right gonads would develop into testes.
Yunqi Jiang   +7 more
doaj   +1 more source

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