Results 111 to 120 of about 62,119 (279)

Critical Evaluation of Methods for the Identification of Aneugens

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The genotoxic potential of chemicals must be evaluated in regulatory safety assessment settings, including but not limited to, the development of new pharmaceuticals, industrial chemicals, food and cosmetic ingredients, and agrochemicals. Initial assessment of the chromosome‐damaging potential of chemicals is often conducted in mammalian cells
Xiaowen Sun, Stephen D. Dertinger, Azeddine Elhajouji, Daniel J. Roberts, Jan van Benthem, Maik Schuler, Shambhu Roy, Alexandra Taraboletti, Connie L. Chen   +8 more
wiley   +1 more source

Maintenance of a Low Level of Sex Chromatin in One of Uniovular Twins [PDF]

, 1972
W. Konopada
openalex   +1 more source

The single-cell chromatin landscape in gonadal cell lineage specification

BMC Genomics
Gonad development includes sex determination and divergent maturation of the testes and ovaries. Recent advances in measuring gene expression in single cells are providing new insights into this complex process.
Hoi Ching Suen, Fanghong Ou, Kai-kei Miu, Zhangting Wang, Wai-yee Chan, Jinyue Liao   +5 more
doaj   +1 more source

Moth sex chromatin probed by comparative genomic hybridization (CGH) [PDF]

, 2003
Ken Sahara, František Marec, Ulrike Eickhoff, Walther Traut   +3 more
openalex   +1 more source

The Sex Chromatin [PDF]

Journal of Medical Genetics, 1967
openaire   +2 more sources

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Genetics, Chromatin Diminution, and Sex Chromosome Evolution in the Parasitic Nematode Genus Strongyloides [PDF]

, 2010
Linda Nemetschke, Alexander G. Eberhardt, Hubertus Hertzberg, Adrian Streit   +3 more
openalex   +1 more source

Sizing and concentration analysis of cfDNA using Biabooster technology: Results from a prospective plasma‐based collection of 77 patients with locally advanced unresectable esophageal cancer

International Journal of Cancer, EarlyView.
What's New? This study introduces a novel approach for detecting locally advanced esophageal carcinoma using cell‐free DNA (cfDNA) analysis through a highly sensitive fragmentome assay. Unlike traditional sequencing‐based methods that are limited by the absence of specific mutations in esophageal tumors, our method offers an alternative by quantifying ...
Anouchka Modesto, Sophie Gibert, Caroline Delmas, David Tougeron, Amaury Paumier, Alexandre Taillez, Samuel Le Sourd, Delphine Argo Leignel, Philippe Ronchin, Ariane Darut Jouve, Véronique Vendrely, Olivier Riou, Jérôme Martin‐Babau, Thomas Leroy, Laurent Quéro, Naïma Hanoun, Pierre Cordelier, Veronica Pezzella, Jean Pierre Delord, Rosine Guimbaud, Elizabeth Moyal, Catherine Seva   +21 more
wiley   +1 more source

The gene regulatory landscape driving mouse gonadal supporting cell differentiation. [PDF]

Sci Adv
Stévant I, Abberbock E, Ridnik M, Weiss R, Swisa L, Futtner CR, Maatouk DM, Lovell-Badge R, Malysheva V, Gonen N.   +9 more
europepmc   +2 more sources

The role of UPR‐related long noncoding RNAs in development of endocrine resistance in breast cancer

International Journal of Cancer, EarlyView.
Abstract Breast cancer patients who express estrogen receptor α (ER) typically receive endocrine therapy as a first‐line treatment. Most ER‐positive breast cancer patients initially respond to endocrine therapy, but up to 40% of patients develop resistance over time, and the main mechanism is aberrant activation of ER signaling pathways.
Wen Liu, Sahil Gupta, Sanjeev Gupta
wiley   +1 more source