Results 121 to 130 of about 60,046 (266)
Genetic variation in NFE2L2 is associated with outcome following aneurysmal subarachnoid haemorrhage
European Journal of Neurology, Volume 30, Issue 1, Page 116-124, January 2023., 2023 Abstract Background and purpose Nuclear factor erythroid 2‐related factor 2 (NRF2; encoded by the NFE2L2 gene) has been implicated in outcome following aneurysmal subarachnoid haemorrhage (aSAH) through its activity as a regulator of inflammation, oxidative injury and blood breakdown product clearance.
Ben Gaastra +10 more
wiley +1 more source
Upregulation of ST3GAL5 predicts suppression of malignant biological behavior in bladder cancer
UroPrecision, EarlyView.Abstract Background Bladder cancer (BLCA) is the most prevalent malignancy in the urinary tract system, while ST3GAL5 is a protein‐coding gene that catalyzes the formation of ganglioside monosialodihexosylganglioside 3 (GM3) synthase. GM3 synthase has been reported to significantly influence the malignant process of various cancers.
Song Ou‐Yang +3 more
wiley +1 more source
Symptomatic narcolepsy in a dog with functional pituitary gland macroadenoma
Veterinary Record Case Reports, EarlyView.Abstract Symptomatic narcolepsy in dogs has been rarely reported. A 7‐year‐old, female, neutered Greek harehound presented with chronic progressive lethargy, dysphonia, episodes of flaccid paralysis of all limbs following excitement or eating, as well as pinnae and tail alopecia, hyperpigmentation and ‘rat tail’.
Christina Koufaki +4 more
wiley +1 more source
Veterinary Record Case Reports, EarlyView.Abstract A 5‐year‐old, male, neutered, domestic short‐haired cat presented for lethargy and anorexia and was diagnosed with a cardiac tumour and likely pulmonary metastases by ultrasonography and contrast computed tomography of the thorax. Clinically, the cat presented with right‐sided heart failure, pleural and pericardial effusion and ensuing ...
Samuel Kalpers, George Smith, Angie Rupp
wiley +1 more source
Multiscale Modeling Primer: Focus on Chromatin and Epigenetics [PDF]
arXivEssential life processes take place across multiple space and time scales in living organisms but understanding their mechanistic interactions remains an ongoing challenge. Advanced multiscale modeling techniques are providing new opportunities and insights into these complex processes.
arxiv
Sex-Based Mhrt Methylation Chromatinizes MeCP2 in the Heart
iScience, 2019 Summary: In the heart, primary microRNA-208b (pri-miR-208b) and Myheart (Mhrt) are long non-coding RNAs (lncRNAs) encoded by the cardiac myosin heavy chain genes.
Harikrishnan K.N. +10 more
doaj
Molecular mechanisms of resistance to tyrosine kinase inhibitor in clear cell renal cell carcinoma
International Journal of Urology, Volume 29, Issue 12, Page 1419-1428, December 2022., 2022 Abstract Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma (RCC). Loss of von Hippel–Lindau tumor suppressor gene is frequently observed in ccRCC and increases the expression of hypoxia‐inducible factors and their targets, including epidermal growth factor, vascular endothelial growth factor, and platelet ...
Yohei Sekino +3 more
wiley +1 more source
Aging Cell, EarlyView.Age‐related differences in EAE outcomes stem from combined peripheral and CNS factors. Key peripheral adaptive immunity changes include altered naïve/memory T cell ratios, Th1 skewing, increased suppressive Tregs, CD4+ T cell exhaustion, enhanced B cell antigen presentation, and reduced NK cell cytotoxicity.
María Dema +6 more
wiley +1 more source
Journal of Cellular and Molecular Medicine, Volume 26, Issue 23, Page 5794-5806, December 2022., 2022 Abstract Breast cancer (BC) is the leading cause of cancer‐related deaths in females worldwide and is related to genetic and environmental factors. Dietary components may strongly influence the risk of BC. A possible association was also reported between the fat mass and obesity‐associated (FTO) single‐nucleotide polymorphisms (SNPs) and BC. This study
Saeid Doaei +15 more
wiley +1 more source