Results 121 to 130 of about 123,835 (338)
ABSTRACT Elastic tethers connect telomeres of separating chromosomes in anaphase of animal cells. Immunofluorescence staining of titin in crane‐fly spermatocytes, using 4 different antibodies, shows that the giant elastic protein titin seems to be a component of mitotic tethers: titin “strands” extend between separating chromosomes, connecting their ...
Demetra Economopoulos+5 more
wiley +1 more source
Age-related changes to lumbosacral spinal cord motoneurons that modulate bladder and bowel functions in male C57BL/6 mice [PDF]
Incontinence and sexual dysfunction are often increased in the aged human population. In rats and mice the pattern of micturition and faecal clearance also changes with ageing and is suggestive of bladder and bowel ...
Black, G.+4 more
core
ABSTRACT Background There is a decreased cervical cancer screening rate among female to male transgender (FTMTG) patients. Data on the distinct cytologic features present in cervical cytology (CC) of those on testosterone therapy is limited. Methods An 2017–2023 electronic database search identified CC specimens from a cohort of FTMTG patients on ...
Juanita E. Ferreira+6 more
wiley +1 more source
URIDINE-5-H3 RADIOAUTOGRAPHY OF THE HUMAN SEX CHROMATIN BODY [PDF]
David E. Comings
openalex +1 more source
Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby
Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe+3 more
wiley +1 more source
A survey of sex chromatin abnormalities in mental hospitals. [PDF]
N. Maclean+4 more
openalex +1 more source
A pilot study on DNA methylation changes for non‐invasive molecular diagnostics in heart failure
A liquid biopsy approach integrating the high‐resolution RRBS DNA methylation platform and network‐oriented strategy identified the hypomethylation of CPTA1, CKAP4, SPTB, SYT6, EIF2S2, and RAB11FIP1 genes as useful biomarkers in distinguishing between ischaemic and non‐ischaemic HF aetiologies.
Giuditta Benincasa+7 more
wiley +1 more source
INO80 regulates chromatin accessibility to facilitate suppression of sex-linked gene expression during mouse spermatogenesis [PDF]
Prabuddha Chakraborty, Terry Magnuson
openalex +1 more source
The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches
Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori+9 more
wiley +1 more source
Critical Evaluation of Methods for the Identification of Aneugens
ABSTRACT The genotoxic potential of chemicals must be evaluated in regulatory safety assessment settings, including but not limited to, the development of new pharmaceuticals, industrial chemicals, food and cosmetic ingredients, and agrochemicals. Initial assessment of the chromosome‐damaging potential of chemicals is often conducted in mammalian cells
Xiaowen Sun+8 more
wiley +1 more source