Results 141 to 150 of about 60,046 (266)

Rapid detection of mouse spermatogenic defects by testicular cellular composition analysis via enhanced deep learning model

Andrology, EarlyView.
Abstract Background Histological analysis of the testicular sections is paramount in infertility research but tedious and often requires months of training and practice. Objectives Establish an expeditious histopathological analysis of mutant mice testicular sections stained with commonly available hematoxylin and eosin (H&E) via enhanced deep learning
Nianfei Ao, Min Zang, Yue Lu, Yiping Jiao, Haoda Lu, Chengfei Cai, Xiangxue Wang, Xin Li, Minge Xie, Tingting Zhao, Jun Xu, Eugene Yujun Xu   +11 more
wiley   +1 more source

Meiotic dynamics in a unique Australian marsupial provide new insights into the evolution of neo-sex chromosomes in the early stages of differentiation. [PDF]

Front Cell Dev Biol
Marín-Gual L, Hogg CJ, Chang JK, Pask AJ, Renfree MB, Waters PD, Ruiz-Herrera A.   +6 more
europepmc   +1 more source

EP300‐interacting inhibitor of differentiation 3 is required for spermatogenesis in mice

Andrology, EarlyView.
Abstract Background Mammalian spermatogenesis is a highly complex process of cell proliferation, meiosis, and differentiation. A series of genes are expressed in an orderly and precise manner to ensure spermatogenesis, with chromatin undergoing intricate changes throughout.
Ping Zhang, Longsheng Zhang, Li Yu, Xinli Zhou, Xu Chen, Yuchuan Zhou, Ningling Wang, Hui Zhu   +7 more
wiley   +1 more source

Deciphering the epigenetic role of long non-coding RNAs in mood disorders: Focus on human brain studies. [PDF]

Clin Transl Med
Roy B, Verma AK, Funahashi Y, Dwivedi Y.
europepmc   +1 more source

Semen cryopreservation and storage in liquid nitrogen: Impact on chromatin compaction

Andrology, EarlyView.
Abstract Background Sperm cryopreservation is a consolidate option for long‐term male fertility preservation. The freezing/thawing procedure causes detrimental effects to spermatozoa, including damage to viability, motility, membrane composition, and DNA, whereas the effect on sperm chromatin compaction is less studied.
Lara Tamburrino, Giulia Traini, Maria Emanuela Ragosta, Sara Dabizzi, Sara Vezzani, Flavia Scarpa, Linda Vignozzi, Elisabetta Baldi, Sara Marchiani   +8 more
wiley   +1 more source

Editorial: Regulatory mechanisms of gene expression, chromatin structure and nuclear dynamics in gametogenesis

Frontiers in Cell and Developmental Biology, 2022
Soichiro Yamanaka, Satoshi H. Namekawa, Kei-ichiro Ishiguro   +2 more
doaj   +1 more source

A WHO 2021‐based comprehensive scheme outlining sperm parameters’ associations with IVF outcomes in PGT‐A cycles

Andrology, EarlyView.
Abstract Objective To examine the association between semen parameters, assessed according to World Health Organization (WHO)‐2021 criteria, and paternal body mass index (BMI) and age, with embryological and clinical outcomes in ICSI cycles involving preimplantation genetic testing for aneuploidy (PGT‐A).
Rossella Mazzilli, Danilo Cimadomo, Federica Innocenti, Marilena Taggi, Greta Chiara Cermisoni, Sara Ginesi, Lisa Dovere, Laura Albricci, Maurizio Guido, Maria Rosaria Campitiello, Susanna Ferrero, Antonio Capalbo, Alberto Vaiarelli, Filippo Maria Ubaldi, Alberto Ferlin, Laura Rienzi, Gianluca Gennarelli   +16 more
wiley   +1 more source

Three-dimensional genome structures of single mammalian sperm. [PDF]

Nat Commun
Xu H, Chi Y, Yin C, Li C, Chen Y, Liu Z, Liu X, Xie H, Chen ZJ, Zhao H, Wu K, Zhao S, Xing D.   +12 more
europepmc   +1 more source

Effects of AZFc (b2/b4, b1/b3, b2/b3, and gr/gr) deletions and primary duplications on the outcomes of the first intracytoplasmic sperm injection treatment cycle: A single‐center retrospective cohort study

Andrology, EarlyView.
Abstract Background Current advances in high‐throughput sequencing technology enable the precise identification of Y chromosome microdeletion and primary duplication in infertile couples, but the mechanism and clinical significance of these mutations in assisted reproductive techniques remain unclear.
Linlin Li, Xiangyin Liu, Xinying Wang, Hongguo Zhang, Ruizhi Liu   +4 more
wiley   +1 more source

A case of CIC‐rearranged sarcoma with CIC‐LEUTX gene fusion in spinal cord

Neuropathology, Volume 42, Issue 6, Page 555-562, December 2022., 2022
A 16‐year‐old male was admitted to the hospital for weakness of both lower extremities. Magnetic resonance imaging revealed an intraspinal extramedullary subdural mass at the thoracic 9 level. Microscopically, the tumor cells were small to medium sized and round to ovoid in shape.
Kun Song, Yu Huang, Chun‐Duo Xia, Hai‐Qing Zhu, Juan Wang   +4 more
wiley   +1 more source