Results 11 to 20 of about 123,835 (338)

The multicopy gene Sly represses the sex chromosomes in the male mouse germline after meiosis. [PDF]

open access: yesPLoS Biology, 2009
Studies of mice with Y chromosome long arm deficiencies suggest that the male-specific region (MSYq) encodes information required for sperm differentiation and postmeiotic sex chromatin repression (PSCR).
Julie Cocquet   +6 more
doaj   +5 more sources

The epigenome of evolving Drosophila neo-sex chromosomes: dosage compensation and heterochromatin formation. [PDF]

open access: yesPLoS Biology, 2013
Sex chromosomes originated from autosomes but have evolved a highly specialized chromatin structure. Drosophila Y chromosomes are composed entirely of silent heterochromatin, while male X chromosomes have highly accessible chromatin and are ...
Qi Zhou   +5 more
doaj   +7 more sources

3D chromatin maps of a brown alga reveal U/V sex chromosome spatial organization [PDF]

open access: greenNature Communications
Nuclear three dimensional (3D) folding of chromatin structure has been linked to gene expression regulation and correct developmental programs, but little is known about the 3D architecture of sex chromosomes within the nucleus, and how that impacts ...
Pengfei Liu   +9 more
doaj   +2 more sources

INO80 regulates chromatin accessibility to facilitate suppression of sex-linked gene expression during mouse spermatogenesis.

open access: goldPLoS Genetics
The INO80 protein is the main catalytic subunit of the INO80-chromatin remodeling complex, which is critical for DNA repair and transcription regulation in murine spermatocytes.
Prabuddha Chakraborty, Terry Magnuson
doaj   +4 more sources

Single-nucleus multiomics reveals the gene regulatory networks underlying sex determination of murine primordial germ cells [PDF]

open access: yeseLife
Accurate specification of female and male germ cells during embryonic development is critical for sexual reproduction. Primordial germ cells (PGCs) are the bipotential precursors of mature gametes that commit to an oogenic or spermatogenic fate in ...
Adriana K Alexander   +7 more
doaj   +2 more sources

A ROLE FOR CELLULAR IMMUNITY IN EARLY POSTPARTUM PERIOD

open access: yesМедицинская иммунология, 2021
The functioning of the secretory organs is closely related to the activity of the immune system. As is well known, this participation is manifested in the fact that at certain stages of activity, the lymphoid cells migrating to the organ can be involved ...
N. A. Panova, V. G. Skopichev
doaj   +1 more source

Correlation between Sex Chromatin and Female Breast Tumour in Paraffin Sections, Buccal Smears and Peripheral Blood Films [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Introduction: Sex chromatin is a plano-convex to triangular DNA mass measuring approximately 1µm in size and lying adjacent to the inner side of nuclear membrane in the somatic cells of the females.
Bodal Vijay Kumar   +7 more
doaj   +1 more source

Plasma growth hormone pulses induce male-biased pulsatile chromatin opening and epigenetic regulation in adult mouse liver

open access: yeseLife, 2023
Sex differences in plasma growth hormone (GH) profiles, pulsatile in males and persistent in females, regulate sex differences in hepatic STAT5 activation linked to sex differences in gene expression and liver disease susceptibility, but little is ...
Andy Rampersaud   +2 more
doaj   +1 more source

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