Ancestral Chromatin Configuration Constrains Chromatin Evolution on Differentiating Sex Chromosomes in Drosophila. [PDF]
Sex chromosomes evolve distinctive types of chromatin from a pair of ancestral autosomes that are usually euchromatic. In Drosophila, the dosage-compensated X becomes enriched for hyperactive chromatin in males (mediated by H4K16ac), while the Y ...
Qi Zhou, Doris Bachtrog
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Impact of 3D genome organization, guided by cohesin and CTCF looping, on sex-biased chromatin interactions and gene expression in mouse liver [PDF]
Several thousand sex-differential distal enhancers have been identified in mouse liver; however, their links to sex-biased genes and the impact of any sex-differences in nuclear organization and chromatin interactions are unknown. To address these issues,
Bryan J. Matthews, David J. Waxman
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The INO80 protein is the main catalytic subunit of the INO80-chromatin remodeling complex, which is critical for DNA repair and transcription regulation in murine spermatocytes.
Prabuddha Chakraborty, Terry Magnuson
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Sex Chromatin Demonstration by A Modified Hair Root Sheath Technique [PDF]
A modified technique for demonstration of sex chromatin in nuclei of hair root sheath has been described and its advantages are discussed.
Ramesh Arora, R. N. Sharma
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Enhanced chromatin accessibility of the dosage compensated Drosophila male X-chromosome requires the CLAMP zinc finger protein. [PDF]
The essential process of dosage compensation is required to equalize gene expression of X-chromosome genes between males (XY) and females (XX). In Drosophila, the conserved Male-specific lethal (MSL) histone acetyltransferase complex mediates dosage ...
Jennifer Urban +8 more
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RANK signaling in osteoclast precursors results in a more permissive epigenetic landscape and sexually divergent patterns of gene expression [PDF]
Background Sex is an important risk factor in the development of osteoporosis and other bone loss disorders, with women often demonstrating greater susceptibility than men. While variation in sex steroids, such as estradiol, accounts for much of the risk,
Abigail L. Keever +4 more
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Differences of size and shape of active and inactive X-chromosome domains in human amniotic fluid cell nuclei [PDF]
It is a widely held belief that the inactive X-chromosome (Xi) in female cell nuclei is strongly condensed as compared to the largely decondensed active X-chromosome (Xa).
Barr +39 more
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Deciphering the Role of the Barr Body in Malignancy: An insight into head and neck cancer
X chromosome inactivation is the epitome of epigenetic regulation and long non-coding ribonucleic acid function. The differentiation status of cells has been ascribed to X chromosome activity, with two active X chromosomes generally only observed in ...
Deepti Sharma +4 more
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UBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells [PDF]
The N-end rule pathway is a proteolytic system in which its recognition components (N-recognins) recognize destabilizing N-terminal residues of short-lived proteins as an essential element of specific degrons, called N-degrons.
An, JY +12 more
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The Effect of Sex Chromatin on Some Reproductive Traits of local Sheep in Erbil
This study was conducted on local sheep belongs to private flock in Erbil plain during the period 4 /11/2011 till 25/10/2012. The investigation included 65 local sheep to study the effect of sex chromatin frequency on the Daily Milk Yield (DMY), weight ...
Nihad Ahmad Ameen Ameen +1 more
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