Results 231 to 240 of about 123,835 (338)

Rewiring of chromatin regulation underlies the evolution of brown algal multicellularity

open access: yes
Vigneau J   +8 more
europepmc   +1 more source

Ancestral genomic functional differences in oligodendroglia: implications for Alzheimer's disease. [PDF]

open access: yesAlzheimers Dement
Ramirez AM   +26 more
europepmc   +1 more source

Canonical and Non‐Canonical Functions of Histone H3K4 Methylation Modifiers in Cancer

open access: yesCancer Science, EarlyView.
Histone H3K4‐modifying enzymes regulate gene expression and cellular processes critical to cancer development. Beyond their canonical roles, these enzymes also exhibit non‐catalytic and non‐histone functions, offering new opportunities for therapeutic intervention. ABSTRACT Histone H3K4 modifications are altered in the regulation of gene expression and
Takayuki Hoshii
wiley   +1 more source

GWAS Identifies SNPs Associated With Severe Adverse Events and Efficacy in Advanced Renal Cell Carcinoma Treated With Nivolumab

open access: yesCancer Science, EarlyView.
This study highlights the importance of germline genetic markers in predicting severe trAEs caused by nivolumab. Our findings support their potential to guide personalized immunotherapy and improve treatment safety and efficacy in advanced ccRCC and other cancers.
Tokiyoshi Tanegashima   +26 more
wiley   +1 more source

Whole genome DNA methylation patterns in tissue and cfDNA associated with fibrosis reflect the complex signature of MASLD. [PDF]

open access: yesPLoS One
Ahn J   +14 more
europepmc   +1 more source

Assessment of Patients With Beta‐Lactams Positive Provocation Tests by Biomarkers of IgG‐Related Neutrophil Activation

open access: yesClinical &Experimental Allergy, EarlyView.
Neutrophil activation in beta‐lactams (BL) immediate hypersensitivity reactions (IHR). Factor component analysis of IHR biomarkers suggests an IgG‐mediated mechanism. We propose Neutrophil Elastase as a biomarker of neutrophil activation in BL IHR. ABSTRACT Background Beta‐lactams (BLs) are the predominant cause of immediate allergic reactions to drugs.
Adrienne Astrid Gallizzi   +13 more
wiley   +1 more source

Sex-specific expression and function of TRIM28 during mouse primordial germ differentiation. [PDF]

open access: yesiScience
DiRusso JA   +8 more
europepmc   +1 more source

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