Background In the post-GWAS era, there is an unmet need to decode the underpinning genetic etiologies of late-onset Alzheimer’s disease (LOAD) and translate the associations to causation.
Julio Barrera+15 more
doaj +1 more source
Additional sex combs interacts with enhancer of zeste and trithorax and modulates levels of trimethylation on histone H3K4 and H3K27 during transcription of hsp70. [PDF]
BACKGROUND: Maintenance of cell fate determination requires the Polycomb group for repression; the trithorax group for gene activation; and the enhancer of trithorax and Polycomb (ETP) group for both repression and activation.
Brock, Hugh W+4 more
core +2 more sources
Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2.
In mitotic cells, establishment of sister chromatid cohesion requires acetylation of the cohesin subunit SMC3 (acSMC3) by ESCO1 and/or ESCO2. Meiotic cohesin plays additional but poorly understood roles in the formation of chromosome axial elements (AEs)
Biswas, U.+6 more
core +1 more source
Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. [PDF]
The mammary epithelium depends on specific lineages and their stem and progenitor function to accommodate hormone-triggered physiological demands in the adult female.
Abe+111 more
core +2 more sources
Sex chromatin of hydatidiform moles. [PDF]
Y.W. Loke
openaire +5 more sources
UV micro-irradiation of the Chinese hamster cell nucleus and caffeine post-treatment immunocytochemical localization of DNA photolesions in cells with partial and generalized chromosome shattering [PDF]
UV micro-irradiation of a small part of the Chinese hamster nucleus and caffeine post-incubation often results in shattered chromosomes at the first post-irradiation mitosis.
Cornelis+26 more
core +1 more source
Role of Sex Chromatin on performance in the Arabi sheep
This study was conducted on 122 Arabi sheep belonged to private flock in Erbil plain Kurdistan region- Iraq, from July/ 2014 to August/ 2015 for studying the role of sex chromatin on daily milk production, total milk production, lactation period ...
Salim Omar Raoof
doaj +1 more source
The Effect of X-Rays on Cytological Traits of Tuta absoluta (Lepidoptera: Gelechiidae) [PDF]
The tomato leafminer, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae) is one of the most important pests of tomato. With the purpose of developing environmentally friendly control tactics such as the inherited sterility (IS) technique against this ...
Cagnotti, Cynthia Lorena+5 more
core +1 more source
Methylation Status of Imprinted Genes and Repetitive Elements in Sperm DNA from Infertile Males [PDF]
Stochastic, environmentally and/or genetically induced disturbances in the genome-wide epigenetic reprogramming processes during male germ-cell development may contribute to male infertility.
El Hajj, N.+7 more
core +1 more source