Results 221 to 230 of about 2,151,922 (308)

Impact of low-level sex chromosome mosaicism (<10%) on clinical outcomes of first fresh embryo transfer: a propensity score-matched retrospective cohort study. [PDF]

Front Endocrinol (Lausanne)
Feng K, Wei H, Luo Y, Li D, Li X, Yang C, Zhou L, Tan S, Zhu L.   +8 more
europepmc   +1 more source

Silver chimaera genome highlights lineage-specific sex chromosome and opsin gene evolution in holocephalans. [PDF]

DNA Res
Teramura A, Kadota M, Hirase S, Kuraku S, Kikuchi K.   +4 more
europepmc   +1 more source

Sizing and concentration analysis of cfDNA using Biabooster technology: Results from a prospective plasma‐based collection of 77 patients with locally advanced unresectable esophageal cancer

International Journal of Cancer, EarlyView.
What's New? This study introduces a novel approach for detecting locally advanced esophageal carcinoma using cell‐free DNA (cfDNA) analysis through a highly sensitive fragmentome assay. Unlike traditional sequencing‐based methods that are limited by the absence of specific mutations in esophageal tumors, our method offers an alternative by quantifying ...
Anouchka Modesto, Sophie Gibert, Caroline Delmas, David Tougeron, Amaury Paumier, Alexandre Taillez, Samuel Le Sourd, Delphine Argo Leignel, Philippe Ronchin, Ariane Darut Jouve, Véronique Vendrely, Olivier Riou, Jérôme Martin‐Babau, Thomas Leroy, Laurent Quéro, Naïma Hanoun, Pierre Cordelier, Veronica Pezzella, Jean Pierre Delord, Rosine Guimbaud, Elizabeth Moyal, Catherine Seva   +21 more
wiley   +1 more source

Genomic Instability and Clonal Hematopoiesis in the Deep-Space Environment: The Role of Sex-Chromosome Asymmetry and High-LET Radiation. [PDF]

Curr Stem Cell Rep
Zakharyan R, Stepanyan A, Minasyan A, Davitavyan S, Lazaryan G, Hakobyan S, Brojakowska A, Bisserier M, Sahoo S, Zhang S, Garikipati VNS, Khlgatian MK, Arakelyan A, Goukassian DA.   +13 more
europepmc   +1 more source

Gene signatures characterizing driver mutations in lung squamous carcinoma are predictive of the progression of pre‐cancer lesions

International Journal of Cancer, EarlyView.
What's New? Lung squamous cell carcinoma (LUSC) is more aggressive than lung adenocarcinoma, and is most often diagnosed at an advanced stage. Here, the authors evaluated gene expression data from LUSC tumors and came up with gene signatures for 34 genetic abnormalities whose expression changes throughout different precancerous stages. Several of these
Yupei Lin, Venugopalareddy Mekala, Jianrong Li, Xiang Wang, Muhammad Aminu, Jia Wu, Jianjun Zhang, Robert Taylor Ripley, Christopher I. Amos, Chao Cheng   +9 more
wiley   +1 more source

Sex chromosome aneuploidy impacts on human gene expression and regulation: a systematic review. [PDF]

Mol Med
Legue M, Staszewski M, Mastronardo M, Butera G, Dakic A, Raznahan A.   +5 more
europepmc   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Sex chromosome dosage compensation in a sex reversing skink is not influenced by sexual phenotype. [PDF]

BMC Genomics
Hanrahan BJ, Chang JK, Milton AM, Lister NC, Dissanayake DSB, Hammond JM, Reis ALM, Deveson IW, Ruiz-Herrera A, Patel HR, Graves JAM, Georges A, Waters PD.   +12 more
europepmc   +1 more source

Descriptive Analysis of Epidemiology, Demographic Characteristics, and Survival of Dedifferentiated Liposarcoma in France

International Journal of Cancer, EarlyView.
ABSTRACT Dedifferentiated liposarcoma (DDLPS) is a rare soft tissue sarcoma with limited real‐world epidemiologic data. This nationwide retrospective study describes the epidemiology, management, and outcomes of DDLPS in France using the NETSARC+ national sarcoma registry.
Julien Bollard, Nicolas Penel, Thibaud Valentin, Robin Tranchant, Marie Najean, Christophe Maritaz, Maud Toulmonde, Matthieu Faron, Axel Le Cesne, Florence Duffaud, Alice Hervieu, Nelly Firmin, Emmanuelle Bompas, Sixtine De Percin, Christophe Perrin, Pascale Dubray‐Longeras, Thomas Ryckewaert, Françoise Ducimetiere, Claire Chemin, Christophe Bouvier, Magali Morelle, Jean‐Yves Blay, Mehdi Brahmi, Sarah Watson   +23 more
wiley   +1 more source

Correction to: Before the East African radiation: sex chromosome systems in basal haplotilapiine cichlids. [PDF]

Genome Biol Evol
europepmc   +1 more source