Results 51 to 60 of about 974,993 (357)

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Evaluation of Radiomorphometric Indices of Panoramic Images of Mandible to Estimate Gender and Approximate Age [PDF]

Journal of Mashhad Dental School
Background: The evaluation of radiomorphometric indices of the mandible can aid dentists not only in forensic investigations but also in diagnosing developmental abnormalities, age-related changes, and gender-specific characteristics that are crucial for
Seyed Hosein Razavi, Ali Drafshi, Fatemeh Ezoddini, Khalil Sarikhani, Mohammad Khodabakhsh   +4 more
doaj   +1 more source

Accuracy of sex determination for northeastern Pacific Ocean thornyheads (Sebastolobus altivelis and S. alascanus) [PDF]

, 2010
Determining the sex of thornyheads (Sebastolobus alascanus and S. altivelis) can be difficult under field conditions. We assessed our ability to correctly assign sex in the field by comparing results from field observations to results obtained in the ...
Fruh, Erica L., Keller, Aimee, Simon, Victor, Trantham, Jessica   +3 more
core  

The "backdoor pathway" of androgen synthesis in human male sexual development. [PDF]

, 2019
Mammalian sex determination (male versus female) is largely controlled by genes, whereas sex differentiation (development of reproductive structures) is largely controlled by hormones. Work in the 20th century indicated that female external anatomy was a
Auchus, Richard J, Miller, Walter L
core   +2 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Homology in Sex Determination in Two Distant Spiny Frogs, Nanorana quadranus and Quasipaa yei

Animals
Sex determination is remarkably diverse, with frequent transitions between sex chromosomes, in amphibians. Under these transitions, some chromosomes are more likely to be recurrently co-opted as sex chromosomes, as they are often observed across deeply ...
Yu Xiao, Guangjiong Liao, Wei Luo, Yun Xia, Xiaomao Zeng   +4 more
doaj   +1 more source

Differences in Homomorphic Sex Chromosomes Are Associated with Population Divergence in Sex Determination in Carinascincus ocellatus (Scincidae: Lygosominae)

Cells, 2021
Sex determination directs development as male or female in sexually reproducing organisms. Evolutionary transitions in sex determination have occurred frequently, suggesting simple mechanisms behind the transitions, yet their detail remains elusive. Here
Peta Hill, Foyez Shams, Christopher P. Burridge, Erik Wapstra, Tariq Ezaz   +4 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Differentiation of Dmrt1 Z and W Homologs Occurred Independently in Two Gekko hokouensis Populations

Biomolecules
Gekko hokouensis is a gecko species widely distributed across East Asia. Although most of the Japanese populations possess ZW sex chromosomes (female heterogamety), the degree of sex chromosome differentiation varies among populations.
Momoka Senga, Nao Kaneko, Yoichi Matsuda, Kazumi Matsubara   +3 more
doaj   +1 more source

Dmrt1 polymorphism covaries with sex-determination patterns in Rana temporaria. [PDF]

, 2016
Patterns of sex-chromosome differentiation and gonadal development have been shown to vary among populations of Rana temporaria along a latitudinal transect in Sweden.
Alho, Beukeboom, Brelsford, Brelsford, Brelsford, Brelsford, Cano, Devlin, Dufresnes, Eggert, Evans, Gosner, Goudet, Gramapurohit, Graves, Grossen, Guerrero, Haczkiewicz, Hillis, Hsü, Matsuba, Matsuba, Matsuda, Miura, Nanda, O'Meally, Ogielska, Perrin, Pflüger, R Core Team, Rodrigues, Rodrigues, Rodrigues, Rodrigues, Schartl, Schmid, Schmid, Schmid, Smith, Somers, Stöck, Stöck, Sumida, Swingle, Volff, Voorrips, Witschi, Witschi, Yoshimoto   +48 more
core   +3 more sources