Results 111 to 120 of about 283,241 (311)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Bioinformatics and transcriptomics to uncover the sex determination in the sand fly species Phlebotomus perniciosus, a major Old World vector of Leishmania infantum.

, 2015
In the Old World, the sand fly Phlebotomus perniciosus is the main vector of Leishmania infantum, the parasitic protozoan that causes visceral and cutaneous leishmaniases in humans and canine reservoir host, as well as, of known and emerging arboviruses ...
PETRELLA, VALERIA, SALVEMINI, MARCO, Volf, P., ACETO, SERENA, Robinson, M., Sanges, R., Cicotti, G., Colonna, V., Benes, V., Perrini, S.   +9 more
core  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Sex determination and temperature-induced sex differentiation in three natural populations of Nile tilapia (Oreochromis niloticus) adapted to extreme temperature conditions

, 2006
As a species of major interest for aquaculture, the sex determination system (SDS) of Nile tilapia, Oreochromis niloticus, has been widely investigated. In this species, sex determination is considered to be governed by the interactions between a complex
Chevassus-Au-Louis, Bernard, Clota, Frédéric, Baroiller, Jean-Francois, Bezault, Etienne, Derivaz, Martial, Chevassus, Bernard   +5 more
core   +1 more source

Differential regulation drives plasticity in sex determination gene networks

BMC Evolutionary Biology, 2010
Background Sex determination networks evolve rapidly and have been studied intensely across many species, particularly in insects, thus presenting good models to study the evolutionary plasticity of gene networks.
Seymour Robert M, MacCarthy Thomas, Pomiankowski Andrew   +2 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Gene discovery in the Old World Leishmania vector Phlebotomus perniciosus (Diptera, Psychodidae): de novo assembly and digital gene expression analysis of sexed transcriptomes from a laboratory strain and Ischia island natural populations.

, 2014
In the Old World, the sand fly Phlebotomus perniciosus is the main vector of Leishmania infantum, the parasitic protozoan that causes visceral and cutaneous leishmaniases in humans and canine reservoir host, as well as, of known and emerging arboviruses ...
PETRELLA, VALERIA, SALVEMINI, MARCO, SACCONE, GIUSEPPE, ACETO, SERENA, MECCARIELLO, ANGELA, Sanges R, Colonna V   +6 more
core  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Metric determination of sex from the humerus in a Guatemalan forensic sample

, 2005
The absence of population-specific standards for sex, age and stature estimation for rural Guatemala is problematic for the forensic analysis of skeletal remains recovered from clandestine graves attributed to the recent armed conflict in that country ...
Ríos Frutos, Luis Francisco
core   +1 more source

Morphometric analysis of mandibular ramus for sex determination on digital orthopantomogram.

Journal of forensic dental sciences, 2017
Identification of sex from skeletal remains is an important tool in forensic science. Mandibular ramus can be used for sex determination either on dry mandible or through orthopantomogram (OPG).To determine the sex from mandibular ramus using digital OPG.The morphometric analysis was conducted on mandibular ramus of 1000 digital OPG using Kodak Master ...
More, Chandramani Bhagwan, Vijayvargiya, Ritika, Saha, Nairita   +2 more
openaire   +2 more sources