Results 121 to 130 of about 6,555,717 (296)

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Sex offender treatment providers: registry.

open access: yes, 2000
Directory of mental health professionals in Texas who meet the minimum requirements for training and experience regarding knowledge and experience with the sex offender ...
Texas. Council on Sex Offender Treatment.   +1 more
core  

University Students' Knowledge of and Attitudes toward Sex Offenders and Treatment of Sex Offenders in New Zealand and China [PDF]

open access: yes, 2014
Topics related to sexual offending and sex offenders can provoke a great deal of fear and anxiety in society. Sex offenders are a group of people who are considered to be especially unpleasant and harmful compared to other types of offenders.
Liu, Sen
core  

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Sex Difference and intra-operative tidal volume: Insights

open access: yes, 2021
Sex Difference and intra-operative tidal volume: Insights 
Günenç, Sakize Ferim   +3 more
core  

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

Texas Sex Offender Treatment Providers: Registry Number 1, Addendum A, October 1991

open access: yes, 1991
Directory of mental health professionals in Texas who meet the minimum requirements for training and experience regarding knowledge and experience with the sex offender ...
Texas. Council on Sex Offender Treatment.
core  

Chronic systemic inflammation by peptidoglycan‐polysaccharide induces skeletal muscle atrophy in male and ovariectomized C57BL/6J mice

open access: yesPhysiological Reports
Chronic systemic inflammation (CSI) induces skeletal muscle atrophy. The severity of tissue damage caused by CSI varies according to sex. However, there are still many unknowns regarding the sex differences in skeletal muscle atrophy in patients with CSI.
Ryoga Kinoshita   +7 more
doaj   +1 more source

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