Results 181 to 190 of about 5,738,044 (300)

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Sex difference in parental risk of suicide attempt during and after pregnancy in Sweden. [PDF]

Nat Hum Behav
Yang Y, Bränn E, Fransson E, László KD, Fang F, Papadopoulos FC, Valdimarsdóttir UA, Skalkidou A, Lu D.   +8 more
europepmc   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Corrigendum: The Aging Slopes of Brain Structures Vary by Ethnicity and Sex: Evidence From a Large Magnetic Resonance Imaging Dataset From a Single Scanner of Cognitively Healthy Elderly People in Korea

Frontiers in Aging Neuroscience, 2020
Yu Yong Choi, Yu Yong Choi, Jang Jae Lee, Kyu Yeong Choi, Eun Hyun Seo, Eun Hyun Seo, IL Han Choo, Hoowon Kim, Hoowon Kim, Hoowon Kim, Min-Kyung Song, Seong-Min Choi, Soo Hyun Cho, Byeong C. Kim, Kun Ho Lee, Kun Ho Lee, Kun Ho Lee   +16 more
doaj   +1 more source

Sex-Difference in Stroke Outcome in Young People in Relation to Haemoglobin Level.

Cerebrovasc Dis
Mazzucco S, Luengo-Fernandez R, Rothwell PM.   +2 more
europepmc   +1 more source

Sexual selection drives sex difference in adult life expectancy across mammals and birds. [PDF]

Sci Adv
Staerk J, Conde DA, Tidière M, Lemaître JF, Liker A, Vági B, Pavard S, Giraudeau M, Smeele SQ, Vincze O, Ronget V, da Silva R, Pereboom Z, Bertelsen MF, Gaillard JM, Székely T, Colchero F.   +16 more
europepmc   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Vaccine sex differences [PDF]

Nature Immunology, 2019
openaire   +2 more sources

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Sex difference in BAT thermogenesis depends on PGC-1α-mediated phospholipid synthesis in mice. [PDF]

Nat Commun
Takeuchi A, Tsujimoto K, Aoki J, Ikeda K, Kono N, Kano K, Niitsu Y, Horino M, Hara K, Okazaki R, Kaneda R, Murakami M, Shiba K, Komiya C, Aoki J, Yamada T.   +15 more
europepmc   +1 more source