Results 71 to 80 of about 5,738,044 (300)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Sex-specific difference for melanoma from immunotherapy advancement

Frontiers in Oncology
BackgroundThe evaluation of melanoma incidence and mortality trends based on population characteristics, with a particular focus on sex differences, is of utmost importance.MethodsThe gender-stratified analysis of melanoma mortality across various ...
Qianqian Li, Qianqian Li, Ying Dong, Yujiao Ma, You Mo, Jupeng Yuan, Jupeng Yuan, Xu Liu, Xu Liu   +8 more
doaj   +1 more source

Sex Differences in Melanoma

Current Epidemiology Reports, 2019
The goal of this review has been to elucidate the sex differences in cancer incidence and mortality in cutaneous melanoma. We have evaluated biological and behavioral research to determine where the critical questions exist.The most recent findings, through 2015, are exploratory in nature but seem to indicate that the differences are more likely due to
Matthew Robert, Schwartz, Li, Luo, Marianne, Berwick   +2 more
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Sex-related difference in food-anticipatory activity of mice

, 2015
The expression of food-anticipatory activity (FAA) is induced by restricted feeding (RF), and its entrainment requires food-entrainable oscillators, the neuroanatomical basis of which is currently unclear.
Li, Zhigang, Sun, Zhong Sheng, Wang, Jundong, Zhao, Mei, Wang, Kangli, Sun, Kevin Kai, Wang, Yan   +6 more
core   +1 more source

The influence of external and internal factors on the squat jump height [PDF]

Fizička Kultura, 2020
Squat jump is an important tool - an exercise that determines power of kinetic chain muscle groups which leads to jump height. Science and practice registered numerous factors that influence the squat jump height, the most important are set out and ...
Klisarić Dragan
doaj  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Adult sex change leads to extensive forebrain reorganization in clownfish

Biology of Sex Differences
Background Sexual differentiation of the brain occurs in all major vertebrate lineages but is not well understood at a molecular and cellular level.
Coltan G. Parker, George W. Gruenhagen, Brianna E. Hegarty, Abigail R. Histed, Jeffrey T. Streelman, Justin S. Rhodes, Zachary V. Johnson   +6 more
doaj   +1 more source

Associations of sex hormone-binding globulin and testosterone with diabetes among men and women (the Saku Diabetes study): a case control study

Cardiovascular Diabetology, 2012
Background Sex hormone-binding globulin (SHBG) levels and sex hormones have been implicated in the pathogenesis of type 2 diabetes and cardiovascular diseases.
Goto Atsushi, Morita Akemi, Goto Maki, Sasaki Satoshi, Miyachi Motohiko, Aiba Naomi, Terauchi Yasuo, Noda Mitsuhiko, Watanabe Shaw   +8 more
doaj   +1 more source