Results 121 to 130 of about 3,546,027 (344)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Sexually dimorphic DNA methylation and gene expression patterns in human first trimester placenta

Biology of Sex Differences
Background Fetal sex and placental development impact pregnancy outcomes and fetal–maternal health, but the critical timepoint of placenta establishment in first trimester is understudied in human pregnancies.
Tania L. Gonzalez, Bryn E. Willson, Erica T. Wang, Kent D. Taylor, Allynson Novoa, Akhila Swarna, Juanita C. Ortiz, Gianna J. Zeno, Caroline A. Jefferies, Kate Lawrenson, Jerome I. Rotter, Yii-Der Ida Chen, John Williams, Jinrui Cui, Mark O. Goodarzi, Margareta D. Pisarska   +15 more
doaj   +1 more source

The Peahen’s Tale, or Dressing Our Parts at Work [PDF]

, 2007
However, there may ultimately be no logical way to reconcile decisions that prohibit employers from requiring women to wear revealing outfits and others that permit employers to require them to wear makeup,20 or decisions that prohibit penalizing a woman
Seaman, Julie A.
core   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

The Four Core Genotypes mouse model: evaluating the impact of a recently discovered translocation

Biology of Sex Differences
The Four Core Genotypes (FCG) mouse model has become a valuable model to study the mechanistic basis for biological sex differences. This model allows discrimination between influences of gonadal sex (ovaries or testes) from those associated with genetic
Carrie B. Wiese, Barbara Soliman, Karen Reue   +2 more
doaj   +1 more source

POS0362 SEX-RELATED DIFFERENCES IN CHARACTERISTICS AND MORTALITY OF PATIENTS WITH RHEUMATOID ARTHRITIS AND CONCOMITANT HEART FAILURE [PDF]

, 2023
T. Rudi, Vera Zietemann, Yvette Meißner, M. Schneider, M. Worsch, Anja Strangfeld   +5 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

The impact of chronic intermittent hypoxia on enzymatic activity in memory-associated brain regions of male and female rats

Biology of Sex Differences
Background Obstructive sleep apnea (OSA) is an intermittent hypoxia disorder associated with cognitive dysfunction, including learning and memory impairments.
Steve Mabry, Jessica L. Bradshaw, Jennifer J. Gardner, E. Nicole Wilson, Janak Sunuwar, Hannah Yeung, Sharad Shrestha, J. Thomas Cunningham, Rebecca L. Cunningham   +8 more
doaj   +1 more source

Vaccine sex differences [PDF]

Nature Immunology, 2019
openaire   +2 more sources

543. Sex Differences in Clinical Presentation and Outcomes of Adults Hospitalized with COVID-19 Pneumonia After Administration of Infliximab, Abatacept or Cenicriviroc: Subgroup Analysis from the ACTIV-1 Master Protocol [PDF]

, 2023
Adriana M. Rauseo, Tatyana Der, Radica Z. Alicic, Bindu Balani, Caryn G. Morse, Pearl Zakroysky, Linda K. Shaw, Jane C. Atkinson, William G. Powderly   +8 more
openalex   +1 more source