Results 111 to 120 of about 4,553,166 (361)
, 2012 Multicellular animals are a diverse lot, with widely varied body plans and lifestyles. One feature they share, however, is a nearly universal reliance on sexual reproduction for species propagation.
Gamble, Tony
core +1 more source
The sexual identity of adult intestinal stem cells controls organ size and plasticity
, 2015 Sex differences in physiology and disease susceptibility are commonly attributed to developmental and/or hormonal factors, but there is increasing realization that cell-intrinsic mechanisms play important and persistent roles.
Hudry, B, Khadayate, S, Miguel-Aliaga, I
core +1 more source
Hawaiian Picture‐Winged Drosophila Exhibit Adaptive Population Divergence along a Narrow Climatic Gradient on Hawaii Island [PDF]
, 2019 1. Anthropogenic influences on global processes and climatic conditions are increasingly affecting ecosystems throughout the world. 2. Hawaii Island’s native ecosystems are well studied and local long‐term climatic trends well documented, making these ...
Bellinger, M. Renee +2 more
core +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Frontiers in Genetics, 2019 The sex of Chinese tongue sole (Cynoglossus semilaevis) is determined by both genetic sex determination (GSD) and environmental sex determination (ESD), making it an ideal model to study the relationship between sex-determination and temperature.
Qian Wang +16 more
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Frontiers in Physiology, 2018 Recently, the crustacean female sex hormone (CFSH), which is considered a female-specific hormone, has been shown to play a crucial role in female phenotypes in crustaceans.
An Liu +6 more
doaj +1 more source
Epigenetic Regulation of Flower Development in the Oil Palm. W490 [PDF]
, 2012 The mantled floral phenotype which occurs in somatic embryo-derived oil palms (Elaeis guineensis Jacq.) shows detrimental consequences on the large scale production of clonal planting material for this strategic oil crop.
Beulé, Thierry +4 more
core
Testosterone Influence on Gene Expression in Lacrimal Glands of Mouse Models of Sjögren Syndrome [PDF]
, 2019 Purpose: Sjögren syndrome is an autoimmune disorder that occurs almost exclusively in women and is associated with extensive inflammation in lacrimal tissue, an immune-mediated destruction and/or dysfunction of glandular epithelial cells, and a ...
Kam, Wendy R. +6 more
core +2 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source