Results 71 to 80 of about 1,184,749 (314)

A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits [PDF]

, 2002
We tested the hypothesis that genes encoded on the sex chromosomes play a direct role in sexual differentiation of brain and behavior. We used mice in which the testis-determining gene (Sry) was moved from the Y chromosome to an autosome (by deletion of ...
Robin Lovell-Badge, De Vries, Geert, Auger, CJ, Lovell-Badge, R, Catherine J. Auger, Elka M. Scordalakes, Swain, A, Simerly, Richard B., Lovell-Badge, Robin, Richard B. Simerly, Amanda Swain, Arnold, Arthur P., Simerly, RB, Burgoyne, PS, Scordalakes, Elka M., Emilie F. Rissman, Geert J. De Vries, Liang-Yo Yang, Burgoyne, Paul S., Yang, Liang-Yo, Yang, L-Y, Rissman, EF, Rissman, Emilie F., Paul S. Burgoyne, De Vries, G, Arnold, AP, Arthur P. Arnold, Scordalakes, EM, Swain, Amanda, Auger, Catherine J.   +29 more
core   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Prevalence and incidence of sarcoidosis in Korea: a nationwide population-based study

Respiratory Research, 2018
Background The prevalence and incidence of sarcoidosis varies worldwide. We estimated the prevalence and incidence of sarcoidosis in Korea using nationwide claims data from the Korean Health Insurance Review and Assessment Service.
Hee-Young Yoon, Hyeong Min Kim, Ye-Jee Kim, Jin Woo Song   +3 more
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Age and sex distribution trends of SARS-CoV-2 infections: Insights from three epidemic waves in Puducherry, India

Journal of Infection in Developing Countries
Introduction: This study analyzed the age and sex distribution of COVID-19 patients during the initial three COVID-19 waves in Puducherry, India, from August 2020 to March 2022, to understand the distribution of infection across different demographic ...
Lourduraj John De Britto, Arya Rahul, Dinesh Sundaram, Balakrishnan Vijayakumar, Thirumal Sankari, Muthukumaravel Subramanian, Raja Jeyapal Dinesh, Philip Raj Abraham, Panneer Devaraju, Yasin Nazeer, Ayyanar Elango, Balasubramaniyan Ramalingam, Kulandaisamy Athisaya Mary, Suchi Tyagi, Rituraj Niranjan, Paramasivan Rajaiah, Mayilsamy Muniaraj, Narendran Pradeep Kumar, Irudayaraj Geetha, Ananganallur Nagarajan Shriram, Adinarayanan Srividya, Vijesh Sreedhar Kuttiatt, Ashwani Kumar   +22 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Prevalence of work-related musculoskeletal disorders among beach workers

Frontiers in Public Health
ObjectiveTo evaluate the prevalence of repetitive strain injuries (RSIs)/work-related musculoskeletal disorders (WMSDs) and their potential demographic, economic and occupational determinants among urban beach workers in Salvador, Bahia, Brazil, between ...
Mariela Sousa dos Santos, Jailma dos Santos Silva, Jailma dos Santos Silva, Wiler de Paula Dias, Thayane Silva Nunes, Joelma Marques Rodrigues, Adedayo Michael Awoniyi, Cleber Cremonese   +7 more
doaj   +1 more source

Sex determination in Bonellia viridis (Echiura : Bonelliidae) : population dynamics and evolution [PDF]

, 2005
In the echiuran worm Bonellia viridis Rolando, the vast majority of sexually undifferentiated larvae metamorphose into dwarf males that live inside the female when exposed to females, but differentiate into females when developing in the absence of ...
David S. Boukal, Ludek Berec, Berec, Ludek, Patrick J. Schembri, Boukal, David S., Schembri, Patrick J.   +5 more
core   +1 more source