Results 171 to 180 of about 6,794,176 (338)

PP2Acα Deficiency in Vascular Smooth Muscle Cells Accelerates Aortic Aneurysm and Dissection by Regulating KLF4 Phosphorylation and Ubiquitination

Advanced Science, EarlyView.
Vascular smooth muscle cells (VSMCs)‐specific deficiency of PP2Acα exacerbates aortic aneurysm and dissection (AAD) by promoting phenotypic switching through AKT1‐mediated phosphorylation and stabilization of Kruppel‐like factor 4 (KLF4). Reduced PP2Acα enhances KLF4 ubiquitination resistance, suppressing VSMC contractile genes and accelerating aortic ...
Wei‐Peng Hu, Ze‐Yu Cai, Qing‐Le Li, Tao Zhang, Xiang‐Yu Chu, Chang Wang, Qing‐Yi Zhang, Rong Qi   +7 more
wiley   +1 more source

Perceptions of sex education among college students: A case study of a medical school. [PDF]

World J Psychiatry
Lv SY, Bao ZC, Liu ZD, Zhang Y, Gu YL, Li BK, Deng YS, Zhang YJ, Zhang Y.   +8 more
europepmc   +1 more source

Synergistic interactions of obesity with sex, education, and smoking and accumulation of multi-morbidity (MM) across the lifespan. [PDF]

J Multimorb Comorb, 2023
St Sauver JL, Grossardt BR, Chamberlain AM, Kapoor E, Rocca WA.   +4 more
europepmc   +1 more source

Nanoparticle‐Mediated CXCL12–CXCR4 Inhibition Reprograms Macrophages and Suppresses Gastric Carcinoma

Advanced Science, EarlyView.
Molecular mechanism study of self‐assembled M2pep‐Cs NPs/Plerixafor nanoparticles in targeting MΦ reprogramming by regulating the CXCL12–CXCR4 signaling pathway to enhance immune recognition and clearance of GC (Created by BioRender). Abstract Gastric carcinoma (GC) remains a major global health challenge, requiring novel therapeutic approaches.
Qianqian Cao, Xiaolei Cheng, Rongbin Lv, Dianshui Sun, Jihua Wang, Runjia Fu, Rumei Gong, Yueying Xiao, Qin Liu, Xiaomei Li   +9 more
wiley   +1 more source

Invisible glue, holding space and the puzzle pieces of solidarity: United States funding and sex workers in South Africa

South African Journal of Science
Marlise Richter, Constance Mathe
doaj   +1 more source

Sex education to an adolescent male with Down syndrome in a single-mother family in Japan. [PDF]

Pediatr Int
Saito A, Sato T, Shima H, Yamagishi H, Narumi S, Ishii T, Hasegawa T.   +6 more
europepmc   +1 more source

Bridging the Gap Between Family Medicine and Adolescents: Creating Opportunities Through Sex Education. [PDF]

Cureus, 2022
Abreu M, Silva C, Vieira M, Soares R, Pinheiro L.   +4 more
europepmc   +1 more source

Reverse discrimination in higher education: a comparison of the employment of black and white recent doctoral recipients by sex

, 1978
Charles Lee Samuels
openalex   +2 more sources

Effect of social exclusion on the risk of teenage pregnancy: development of hypotheses using baseline data from a randomised trial of sex education [PDF]

, 2003
Chris Bonell
openalex   +1 more source

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

Advanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich, Jing Wang, Ferdinand Althammer, Tim Schubert, Nina Kluck, Valery Grinevich, Stefanie Schmitteckert, Christian P. Schaaf, Gudrun A. Rappold   +8 more
wiley   +1 more source