Results 21 to 30 of about 1,758,122 (189)
FEBS Letters, EarlyView.Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek +15 more
wiley +1 more source
Seroprevalence of toxocariasis in children aged 1-9 years in western Islamic Republic of Iran, 2003 [PDF]
, 2007 We determined the seroprevalence of Toxocara canis infection in 544 children under 10 years randomly selected from urban and rural areas of Hamadan, An enzyme-linked immunosorbent assay was used for detection of antibodies to T.
Azimi, A., Fallah, M., Taherkhani, H.
core +1 more source
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
“I\u27ll do whatever as long as you keep telling me that I’m important”: A case study illustrating the link between adolescent dating violence and sex trafficking victimization [PDF]
, 2015 Background: Approximately 10% of U.S. high school-attending youth are physically abused by a dating partner each year. Many sequelae of dating violence have been documented, but the dating violence literature is lacking information about commercial ...
Bair-Merritt, Megan +2 more
core +1 more source
Gender inequality and sex differences in physical fighting, physical activity, and injury among adolescents across 36 countries [PDF]
, 2019 Purpose: Sex differences in adolescent health are widely documented, but social explanations for these sex differences are scarce. This study examines whether societal gender inequality (i.e., men’s and women’s unequal share in political participation ...
Currie, Candace +4 more
core +2 more sources
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
Sex differences in DNA methylation assessed by 450 K BeadChip in newborns. [PDF]
, 2015 BackgroundDNA methylation is an important epigenetic mark that can potentially link early life exposures to adverse health outcomes later in life.
Barcellos, Lisa +5 more
core +1 more source
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
SEX FACTORS OF THE ADRENAL GLAND [PDF]
Endocrinology, 1940 A LTHOUGH the adrenal gland was the first of the glands of internal secretion to yield a crystalline hormone, with the isolation of adrenalin in 1901 by Takamine and Aldrich, information concerning the various functions of the gland and isolation of the numerous hormones which it undoubtedly contains is still far from complete.
openaire +2 more sources
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song +13 more
wiley +1 more source