Results 41 to 50 of about 1,758,122 (189)
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Factors Related to Intra-Tendinous Morphology of Achilles Tendon in Runners [PDF]
, 2019 The purpose of this study was to determine and explore factors (age, sex, anthropometry, running and injury/pain history, tendon gross morphology, neovascularization, ankle range of motion, and ankle plantarflexor muscle endurance) related to intra ...
Baquet, Ari +6 more
core +4 more sources
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
“There are too many naked pictures found in papers and on the net”: Factors encouraging pre-marital sex among young people of Nepal. [PDF]
, 2010 Background: A conventional Nepalese society still regards sexuality as a taboo and sexual activities outside marriage are rarely accepted. However, attitudes of young Nepalese people towards sexual relationships have steadily changed with the ...
Regmi, Pramod +2 more
core
Measuring quality of care with routine data: avoiding confusion between performance indicators and health outcomes [PDF]
, 1999 Objective To investigate the impact of factors outside the control of primary care on performance indicators proposed as measures of the quality of primary care.
Giuffrida, A, Gravelle, H, Roland, M
core +2 more sources
Hydrogen sulfide repairs testicular damage induced by heat stress in rats
FEBS Open Bio, Volume 15, Issue 6, Page 963-971, June 2025.Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna +4 more
wiley +1 more source
Sex-specific roles of cellular inflammation and cardiometabolism in obesity-associated depressive symptomatology. [PDF]
, 2019 BackgroundObesity and depression are complex conditions with stronger comorbid relationships among women than men. Inflammation and cardiometabolic dysfunction are likely mechanistic candidates for increased depression risk, and their prevalence differs ...
Cabrera, Yesenia +6 more
core +1 more source
The prosocial and antisocial behavior in sport scale [PDF]
, 2009 This research aimed to (a) develop a measure of prosocial and antisocial behavior in sport, (b) examine its invariance across sex and sport, and (c) provide evidence for its discriminant and concurrent validity. We conducted two studies. In study 1, team
Boardley, Ian David, Kavussanu, Maria
core +1 more source