Results 71 to 80 of about 16,852,931 (379)

Factors associated with COVID-19-related death in people with rheumatic diseases: results from the COVID-19 Global Rheumatology Alliance physician-reported registry

open access: yesAnnals of the Rheumatic Diseases, 2021
Objectives To determine factors associated with COVID-19-related death in people with rheumatic diseases. Methods Physician-reported registry of adults with rheumatic disease and confirmed or presumptive COVID-19 (from 24 March to 1 July 2020).
Anja Strangfeld   +36 more
semanticscholar   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Association between eating habits and low physical activity in adolescents [PDF]

open access: yesVojnosanitetski Pregled
Background/Aim. Insufficient levels of physical activity and poor nutrition, have led to an increase in the number of obese adolescents and cardiometabolic problems.
Đurđević Dragan   +3 more
doaj   +1 more source

Estrogen hormone is an essential sex factor inhibiting inflammation and immune response in COVID-19

open access: yesScientific Reports, 2022
Although vaccines have been evaluated and approved for SARS-CoV-2 infection prevention, there remains a lack of effective treatments to reduce the mortality of COVID-19 patients already infected with SARS-CoV-2.
Fuhai Li   +5 more
semanticscholar   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Diversity and the Undertreatment of Pain [PDF]

open access: yes, 2002
The undertreatment of pain is a major public health problem and has enormous costs -- to the individual, the health care system and society. Undertreatment is complex and many studies have clarified the factors that may contribute.
Terry Altilio
core  

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

SEX FACTORS OF THE ADRENAL GLAND [PDF]

open access: yesEndocrinology, 1940
A LTHOUGH the adrenal gland was the first of the glands of internal secretion to yield a crystalline hormone, with the isolation of adrenalin in 1901 by Takamine and Aldrich, information concerning the various functions of the gland and isolation of the numerous hormones which it undoubtedly contains is still far from complete.
openaire   +2 more sources

Evidence for Multiple Sex Factors in the X-Chromosome of Drosophila Melanogaster.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1931
The data presented here permit a decision between two alternative hypotheses regarding sex determination in Drosophila melanogaster. Bridges(1,2,3) has shown that the sex of an individual in this form is determined by a relation between the number of the
Theodosius Dobzhansky, Jack Schultz
semanticscholar   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

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