Results 251 to 260 of about 60,867 (320)
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Sex hormone–binding globulin: biomarker and hepatokine?
Trends in Endocrinology & Metabolism, 2021Over the past decade, there have been important breakthroughs in our understanding of the regulation and function of sex hormone-binding globulin (SHBG). A recent genome-wide association and Mendelian randomization study has provided new insights at the population level.
Pomme I H G, Simons +3 more
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Clinical Endocrinology, 1974
A review was made to understand how plasma binding protein might influence sex-hormone action in target tissues. Steroids are predominately bound to plasma proteins and only unbound steroids enter the cells. Sex-hormone-binding globulin (SHBG) binds to both the main circulating steroid T and E2 but changes in SHBG concentrations exert significant ...
D. Anderson
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A review was made to understand how plasma binding protein might influence sex-hormone action in target tissues. Steroids are predominately bound to plasma proteins and only unbound steroids enter the cells. Sex-hormone-binding globulin (SHBG) binds to both the main circulating steroid T and E2 but changes in SHBG concentrations exert significant ...
D. Anderson
openaire +3 more sources
Sex hormone-binding globulin and polycystic ovary syndrome
Clinica Chimica Acta, 2019Polycystic ovary syndrome (PCOS), one of the most common endocrine diseases that causes infertility in reproductive women, is characterized by hyperandrogenemia, chronic anovulation, and polycystic ovary morphology (PCOM), and most women with PCOS have metabolic abnormalities.
Jing-Ling, Zhu +4 more
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International Journal of Molecular Sciences, 2020 Human sex hormone-binding globulin (SHBG) is a glycoprotein produced by the liver that binds sex steroids with high affinity and specificity. Clinical observations and reports in the literature have suggested a negative correlation between circulating ...
Xianqin Qu, Richard Donnelly
exaly +2 more sources
Dexamethasone suppresses sex-hormone binding globulin
Fertility and Sterility, 1988Dexamethasone suppression (DEX-S) for 14 days has been used to determine the probable source of androgen excess. The exact mechanism(s) of DEX-S is still unclear. The authors postulated that dexamethasone (DEX) inhibits either the synthesis or secretion of sex-hormone binding globulin (SHBG). To examine this hypothesis, 14 women with polycystic ovarian
R E, Blake +3 more
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Sex Hormone Binding Globulin and Aging
Hormone and Metabolic Research, 2008New and more active concepts of steroid binding globulin action are emerging from recent research. As a result, examination of steroid levels in aging humans and the role of steroid binding globulins need to be re-visited. This review will discuss the possibility that sex hormone binding globulin (SHBG) plays an active role in the aging process.
J D, Caldwell, G F, Jirikowski
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Trends in Endocrinology and Metabolism, 2021
Over the past decade, there have been important breakthroughs in our understanding of the regulation and function of sex hormone-binding globulin (SHBG). A recent genome-wide association and Mendelian randomization study has provided new insights at the population level.
Simons, Pomme I. H. G. +3 more
openaire +1 more source
Over the past decade, there have been important breakthroughs in our understanding of the regulation and function of sex hormone-binding globulin (SHBG). A recent genome-wide association and Mendelian randomization study has provided new insights at the population level.
Simons, Pomme I. H. G. +3 more
openaire +1 more source