Results 31 to 40 of about 3,086,890 (203)

Additional file 2 of A genome-wide cross-trait analysis identifies genomic correlation, pleiotropic loci, and causal relationship between sex hormone-binding globulin and rheumatoid arthritis

, 2023
Additional file 2: Fig. S1. Local genetic correlation between crude sex hormone-binding globulin and rheumatoid arthritis. Colored bars represent loci with significant local genetic correlation, covariance, and SNP-heritability after multiple testing ...
Lars Klareskog (4149), Qianwen Liu (721571), Ingrid Kockum (88253), Xia Jiang (210366), Yuan Jiang (296541), Lars Alfredsson (39207)   +5 more
core   +1 more source

Sex hormone-binding globulin in osteoporosis [PDF]

, 2010
Sex hormone-binding globulin (SHBG) is a plasma glycoprotein that binds with high affinity to sex steroids, most notably 5α-dihydrotestosterone, testosterone, and 17β-estradiol, thereby regulating their bioavailability and access to target cells.
M. Audran, M. Royer, B. Bouvard, E. Legrand, E. Hoppé   +4 more
core   +2 more sources

Associations of sex hormone-binding globulin and testosterone with diabetes among men and women (the Saku Diabetes study): a case control study

Cardiovascular Diabetology, 2012
Background Sex hormone-binding globulin (SHBG) levels and sex hormones have been implicated in the pathogenesis of type 2 diabetes and cardiovascular diseases.
Goto Atsushi, Morita Akemi, Goto Maki, Sasaki Satoshi, Miyachi Motohiko, Aiba Naomi, Terauchi Yasuo, Noda Mitsuhiko, Watanabe Shaw   +8 more
doaj   +1 more source

Low serum sex hormone-binding globulin: Marker of inflammation?

, 2014
Background: Low sex hormone-binding globulin (SHBG) is associated with metabolic syndrome (MetS), but its relationship with inflammation is unclear. Methods: This cross-sectional study included 696 subjects (255 men, 235 pre-menopausal women, and 206 ...
林茂欣 ;余宏政 ;李弘元, Liao, Chun-Hou;Li, Hung-Yuan;Yu, Hong-Jeng;Chiang, Han-Sun;Lin, Mao-Shin;Hua, Cyue-Huei;Ma, Wen-Ya   +1 more
core   +1 more source

Sex steroids, growth factors and mammographic density: a cross-sectional study of UK postmenopausal Caucasian and Afro-Caribbean women. [PDF]

, 2009
INTRODUCTION: Sex steroids, insulin-like growth factors (IGFs) and prolactin are breast cancer risk factors but whether their effects are mediated through mammographic density, one of the strongest risk factors for breast cancer, is unknown.
Isabel dos Santos Silva, Dowsett, Mitch, Folkerd, Elizabeth, dos Santos Silva, Isabel, McCormack, VA, Folkerd, E, Perry, Nicholas M, Nichola Johnson, Ben Coupland, Elizabeth Folkerd, Johnson, Nichola, Vinnicombe, Sarah J, Coupland, Ben, Claire Palles, Sarah J Vinnicombe, Palles, C, Jeff M Holly, Coupland, B, Palles, Claire, Holly, Jeff M, Dowsett, M, Johnson, N, dos Santos Silva, I, Valerie A McCormack, Holly, JMP, Vinnicombe, SJ, Mitch Dowsett, McCormack, Valerie A, Perry, NM, Nicholas M Perry   +29 more
core   +2 more sources

Association of sex hormone-binding globulin gene polymorphism and sex hormone-binding globulin levels in postmenopausal women in relation to type 2 diabetes mellitus – A case–Control study

Biomedical and Biotechnology Research Journal, 2023
Background: In women, menopause constitutes the end of a fertile life as a result of ovarian aging. It is characterized by a significant decrease in estrogen concentration along with the change in the body weight, altered distribution of adipose tissue ...
Priya Alva, N Suchetha Kumari, Adithi Bhandary, Lakshmi Manjeera, Neetha Nandan   +4 more
doaj   +1 more source

The Free Hormone Hypothesis: When, Why, and How to Measure the Free Hormone Levels to Assess Vitamin D, Thyroid, Sex Hormone, and Cortisol Status

JBMR Plus, 2021
The free hormone hypothesis postulates that only the nonbound fraction (the free fraction) of hormones that otherwise circulate in blood bound to their carrier proteins is able to enter cells and exert biologic effects.
Daniel D Bikle
doaj   +1 more source

The effect of antiseizure medications on the exposure to combined oral contraceptives: A systematic review and network meta‐analysis

Epileptic Disorders, EarlyView.
Abstract Objective Current recommendations for prescribing combined oral contraceptives (COCs) to people with epilepsy are often conflicting, particularly for weak inducers of cytochrome P450 3A4. We aimed to critically review the literature and compare the antiseizure medication (ASM)‐induced changes in exposure to COC components.
Hagar Cohen, Amnah Omar Mahajna, Tomer Ben‐Shushan, Ilan Matok, Sara Eyal   +4 more
wiley   +1 more source

Free serum cortisol during the postoperative acute phase response determined by equilibrium dialysis liquid chromatography-tandem mass spectrometry [PDF]

, 2003
In severely ill patients low concentrations of the corticosteroid binding globulin are typically found; the aim of this study was to quantify directly free bioactive cortisol concentrations in the sera of postoperative cardiosurgical patients.
Küpper, Christina, Groetzner, Jan, Briegel, Josef, Vogeser, Michael   +3 more
core   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source