Results 1 to 10 of about 460,515 (259)

Targeted metabolomic profiling in rat tissues reveals sex differences [PDF]

open access: yesScientific Reports, 2018
Sex differences affect several diseases and are organ-and parameter-specific. In humans and animals, sex differences also influence the metabolism and homeostasis of amino acids and fatty acids, which are linked to the onset of diseases. Thus, the use of
Margherita Ruoppolo   +9 more
doaj   +2 more sources

The effects of the sex chromosomes on the inheritance of species-specific traits of the copulatory organ shape in Drosophila virilis and Drosophila lummei.

open access: goldPLoS ONE, 2020
The shape of the male genitalia in many taxa is the most rapidly evolving morphological structure, often driving reproductive isolation, and is therefore widely used in systematics as a key character to distinguish between sibling species.
Alex M Kulikov   +5 more
doaj   +3 more sources

Sex separation unveils the functional plasticity of the vomeronasal organ in rabbits

open access: goldFrontiers in Molecular Neuroscience, 2022
Chemosensory cues are vital for social and sexual behaviours and are primarily detected and processed by the vomeronasal system (VNS), whose plastic capacity has been investigated in mice.
Paula R. Villamayor   +6 more
doaj   +2 more sources

Sex Disparities in Organ Donation: Finding an Equitable Donor Pool [PDF]

open access: goldJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background The majority of living organ donors are women, but few are deceased organ donors, which increases risks associated with sex mismatched organs.
Erika Yee   +7 more
doaj   +2 more sources

Sex-stratified osteochondral organ-on-chip model reveals sex-specific responses to inflammatory stimulation

open access: goldMaterials Today Bio
Osteoarthritis (OA) is a musculoskeletal degenerative disease characterized by alterations in cartilage and subchondral bone leading to impaired joint function. OA disproportionally affects females more than males, yet the molecular mechanisms underlying
Francisco Conceição   +9 more
doaj   +2 more sources

Organ-Specific Glucose Uptake: Does Sex Matter?

open access: yesCells, 2022
Glucose uptake by peripheral organs is essential for maintaining blood glucose levels within normal range. Impaired glucose uptake is a hallmark of type 2 diabetes (T2D) and metabolic syndrome and is characterized by insulin resistance.
Adithi Gandhi   +3 more
doaj   +1 more source

Renal transplant: gender differences

open access: yesGiornale di Clinica Nefrologia e Dialisi, 2023
Renal transplantation represents the best treatment for end-stage kidney disease, leading to improved quality of life and life-expectancy for most of the patients.
Anna Laura Fantuzzi   +5 more
doaj   +1 more source

Metronomic Celecoxib Therapy in Clinically Available Dosage Ablates Hepatocellular Carcinoma via Suppressing Cell Invasion, Growth, and Stemness in Pre-Clinical Models

open access: yesFrontiers in Oncology, 2020
ObjectiveTo investigate the anti-carcinogenic effect of metronomic Celecoxib (i.e., frequent administration in clinically available doses) against hepatocellular carcinoma (HCC) in the perspective of metastasis, spontaneous hepatocarcinogenesis, cancer ...
Chun-Chieh Yeh   +15 more
doaj   +1 more source

Sex-specific prevalence and outcomes of frailty in critically ill patients

open access: yesJournal of Intensive Care, 2020
Background The prevalence of frailty, an important risk factor for short- and long-term outcomes in hospitalized adults, differs by sex. Studies in critically ill adults have also found differences in mortality and organ support rates in males and ...
Erin Hessey   +6 more
doaj   +1 more source

Sex differences on solid organ histological characteristics after brain death1 [PDF]

open access: yesActa Cirúrgica Brasileira, 2016
PURPOSE: To investigate gender differences in the evolution of the inflammatory process in rats subjected to brain death (BD). METHODS: Adult Wistar rats were divided into three groups: female; ovariectomized female; and male rats. BD was induced using
Raif Restivo Simão   +7 more
doaj   +2 more sources

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