In‐Depth Analysis of Disease Manifestations in Antineutrophil Cytoplasmic Antibody–Associated Vasculitides Identifies Distinct Clinical Phenotypes [PDF]
ACR Open RheumatologyObjective The antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitides are heterogeneous disorders. The aim of this study was to identify and characterize subgroups of patients based on sex, ANCA, age at diagnosis, and organ involvement ...
Hanna Lindberg +21 more
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Comprehensive microRNA-seq transcriptomic profiling across 11 organs, 4 ages, and 2 sexes of Fischer 344 rats [PDF]
Scientific Data, 2022 Measurement(s) miRNA expression profiling Technology Type(s) Next Generation Sequencing Factor Type(s) organ • age • sex Sample Characteristic - Organism Rattus ...
Xintong Yao +18 more
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Sex-stratified osteochondral organ-on-chip model reveals sex-specific responses to inflammatory stimulation [PDF]
Materials Today BioOsteoarthritis (OA) is a musculoskeletal degenerative disease characterized by alterations in cartilage and subchondral bone leading to impaired joint function. OA disproportionally affects females more than males, yet the molecular mechanisms underlying
Francisco Conceição +9 more
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Sex separation unveils the functional plasticity of the vomeronasal organ in rabbits [PDF]
Frontiers in Molecular Neuroscience, 2022 Chemosensory cues are vital for social and sexual behaviours and are primarily detected and processed by the vomeronasal system (VNS), whose plastic capacity has been investigated in mice.
Paula R. Villamayor +6 more
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PLoS ONE, 2020 The shape of the male genitalia in many taxa is the most rapidly evolving morphological structure, often driving reproductive isolation, and is therefore widely used in systematics as a key character to distinguish between sibling species.
Alex M Kulikov +5 more
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Sex-based Differences and Comparative Predictive Value of MELD 3.0 in Simultaneous Liver-Kidney Transplantation Waitlist Outcomes After Standardization of Listing Criteria in the United States [PDF]
Transplantation DirectBackground. Sex disparities in solid organ transplantation are well documented. Relative changes in sex-based outcome disparities after the 2017 standardization of simultaneous liver-kidney (SLK) listing criteria in the United States have not been ...
Emily A. Leven, MD +4 more
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The sex of organ geometry [PDF]
NatureAbstractOrgans have a distinctive yet often overlooked spatial arrangement in the body1–5. We propose that there is a logic to the shape of an organ and its proximity to its neighbours. Here, by using volumetric scans of many Drosophila melanogaster flies, we develop methods to quantify three-dimensional features of organ shape, position and ...
Laura Blackie +17 more
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BMC Genomics, 2017 Background TEs pervade mammalian genomes. However, compared with mice, fewer studies have focused on the TE expression patterns in rat, particularly the comparisons across different organs, developmental stages and sexes.
Yongcheng Dong +7 more
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The dynamic regulatory network of stamens and pistils in papaya [PDF]
BMC Plant BiologyBackground Papaya exhibits three sex types: female (XX), male (XY), and hermaphrodite (XYh), making it an unusual trioecious model for studying sex determination.
Tao Xiang +8 more
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Systematic Sex-Based Inequity in the MELD Score-Based Allocation System for Liver Transplantation in Germany [PDF]
Transplant InternationalIn liver allocation systems based on the Model for End-stage Liver Disease (MELD) score, sex inequities have been identified in countries with high organ donation rates.
Leke Wiering +16 more
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