Results 1 to 10 of about 3,431,915 (390)

Sex Disparities in Organ Donation: Finding an Equitable Donor Pool [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background The majority of living organ donors are women, but few are deceased organ donors, which increases risks associated with sex mismatched organs.
Erika Yee, Seyedeh Maryam Hosseini, Bianca Duarte, Shannon M. Knapp, Molly Carnes, Bessie Young, Nancy K. Sweitzer, Khadijah Breathett   +7 more
doaj   +3 more sources

Direct evidence supporting Darwin's hypothesis of cross-pollination promoted by sex organ reciprocity. [PDF]

New Phytol, 2022
Summary The floral phenotype plays a main role in the attraction and fit of pollinators. Both perianth traits and the positioning of sex organs can be subjected to natural selection and determine nonrandom mating patterns in populations.
Simón-Porcar VI, Muñoz-Pajares AJ, de Castro A, Arroyo J.   +3 more
europepmc   +2 more sources

The sex of organ geometry

Nature
AbstractOrgans have a distinctive yet often overlooked spatial arrangement in the body1–5. We propose that there is a logic to the shape of an organ and its proximity to its neighbours. Here, by using volumetric scans of many Drosophila melanogaster flies, we develop methods to quantify three-dimensional features of organ shape, position and ...
Laura Blackie, Pedro Gaspar, Salem Mosleh, Oleh Lushchak, Lingjin Kong, Yuhong Jin, Agata P. Zielinska, Boxuan Cao, Alessandro Mineo, Bryon Silva, Tomotsune Ameku, Shu En Lim, Yanlan Mao, Lucía Prieto-Godino, Todd Schoborg, Marta Varela, L. Mahadevan, Irene Miguel-Aliaga   +17 more
semanticscholar   +5 more sources

Targeted metabolomic profiling in rat tissues reveals sex differences [PDF]

Scientific Reports, 2018
Sex differences affect several diseases and are organ-and parameter-specific. In humans and animals, sex differences also influence the metabolism and homeostasis of amino acids and fatty acids, which are linked to the onset of diseases. Thus, the use of
Margherita Ruoppolo, Marianna Caterino, Lucia Albano, Rita Pecce, Maria Grazia Di Girolamo, Daniela Crisci, Michele Costanzo, Luigi Milella, Flavia Franconi, Ilaria Campesi   +9 more
doaj   +2 more sources

Estrogen-related mechanisms in sex differences of hypertension and target organ damage

Biology of Sex Differences, 2020
Hypertension (HTN) is a primary risk factor for cardiovascular (CV) events, target organ damage (TOD), premature death and disability worldwide. The pathophysiology of HTN is complex and influenced by many factors including biological sex.
Andrea Rodrigues Sabbatini, Georgios Kararigas   +1 more
doaj   +2 more sources

Synergistic disruption of external male sex organ development by a mixture of four antiandrogens [PDF]

Environmental Health Perspectives, 2009
Reproduced with permission from Environmental Health Perspectives.Background: By disrupting the action of androgens during gestation, certain chemicals present in food, consumer products, and the environment can induce irreversible demasculinization and ...
Andreas Kortenkamp, Anne Marie Vinggaard, COT, Hib J, Majken Dalgaard, Marta Axelstad, Martin Scholze, National Research Council, Sofie Christiansen, U.S. EPA, U.S. EPA, U.S. EPA (Environmental Protection Agency), Ulla Hass, VKM (Vitenskapskomiteen for Mattrygghet), Vonesh E   +14 more
core   +4 more sources

Hearts apart: sex differences in cardiac remodeling in health and disease

The Journal of Clinical Investigation
Biological sex is an important modifier of physiology and influences pathobiology in many diseases. While heart disease is the number one cause of death worldwide in both men and women, sex differences exist at the organ and cellular scales, affecting ...
Thomas G. Martin, Leslie A. Leinwand
doaj   +2 more sources

Proteome organ aging and cardiometabolic risk in a population at risk for heart failure [PDF]

Cardiovascular Diabetology
Background Biological aging varies across individuals and tissues, influencing chronic diseases, including heart failure (HF). Emerging proteome techniques enable quantification of organ-specific aging acceleration (OAA), but whether OAA relates to HF ...
Kaiyong Qu, Elisa Dal Canto, Anne-Mar L. N. van Ommen, Sabrina Abou Kamar, Arco J. Teske, Maarten Jan Cramer, Marianne C. Verhaar, Dirk J. Duncker, Frans H. Rutten, Isabella Kardys, Roxana Menken, Leonard Hofstra, Igor I. Tulevski, G. Aernout Somsen, N. Charlotte Onland-Moret, Ernest Diez Benavente, Hester M. den Ruijter   +16 more
doaj   +2 more sources

Sex Differences in Excess Mortality Among Waitlisted Kidney, Heart, and Liver Transplant Candidates [PDF]

Transplantation Direct
Background. Sex differences in excess mortality risk (ie, above expected in the age-, sex-, and race-matched general population) among candidates waitlisted for transplant may reflect sex bias in access to the waitlist, disparities in allocation policies,
Amanda Jean Vinson, MD, MSc, Xun Zhang, PhD, Lauren T. Grinspan, MD, Bethany J. Foster, MD, MSc   +3 more
doaj   +2 more sources

Sex-biased gene expression across mammalian organ development and evolution

Science, 2023
Sexually dimorphic traits are common among mammals and are specified during development through the deployment of sex-specific genetic programs. Because little is known about these programs, we investigated them using a resource of gene expression ...
Leticia Rodríguez-Montes, S. Ovchinnikova, Xuefei Yuan, Tania Studer, Ioannis Sarropoulos, S. Anders, H. Kaessmann, Margarida Cardoso-Moreira   +7 more
semanticscholar   +1 more source