Results 131 to 140 of about 460,515 (259)

Proteome organ aging and cardiometabolic risk in a population at risk for heart failure

Cardiovascular Diabetology
Background Biological aging varies across individuals and tissues, influencing chronic diseases, including heart failure (HF). Emerging proteome techniques enable quantification of organ-specific aging acceleration (OAA), but whether OAA relates to HF ...
Kaiyong Qu, Elisa Dal Canto, Anne-Mar L. N. van Ommen, Sabrina Abou Kamar, Arco J. Teske, Maarten Jan Cramer, Marianne C. Verhaar, Dirk J. Duncker, Frans H. Rutten, Isabella Kardys, Roxana Menken, Leonard Hofstra, Igor I. Tulevski, G. Aernout Somsen, N. Charlotte Onland-Moret, Ernest Diez Benavente, Hester M. den Ruijter   +16 more
doaj   +1 more source

Sex and Breed-Dependent Organ Development and Metabolic Responses in Foetuses from Lean and Obese/Leptin Resistant Swine

, 2013
Laura Torres-Rovira, Anne Couturier‐Tarrade, Susana Astiz, Eve Mourier, Mariluz Perez-Solana, Paloma De la Cruz‐Vigo, Ernesto Gómez‐Fidalgo, Raúl Sánchez Sánchez, Pascale Chavatte‐Palmer, Antonio Gonzalez‐Bulnes   +9 more
openalex   +2 more sources

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

Advanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han, Dae‐Seong Lee, Su‐Won Jeong, Ji‐Hyun Yun, Seomin Kang, Seoyoung Jang, EunAh Lee, Ju Hye Baek, Che Ok Jeon, Jin‐Woo Bae   +9 more
wiley   +1 more source

Sex Differences in Vital Organ Support Provided to ICU Patients*

, 2023
Lucy Modra, Alisa M. Higgins, David Pilcher, Michael Bailey, Rinaldo Bellomo   +4 more
openalex   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

The dynamic regulatory network of stamens and pistils in papaya

BMC Plant Biology
Background Papaya exhibits three sex types: female (XX), male (XY), and hermaphrodite (XYh), making it an unusual trioecious model for studying sex determination.
Tao Xiang, Yating Zhu, Yang Wang, Xi Chen, Zhibin Zhang, Juan Lai, Ping Zhou, Ray Ming, Jingjing Yue   +8 more
doaj   +1 more source

Systematic Sex-Based Inequity in the MELD Score-Based Allocation System for Liver Transplantation in Germany

Transplant International
In liver allocation systems based on the Model for End-stage Liver Disease (MELD) score, sex inequities have been identified in countries with high organ donation rates.
Leke Wiering, Leke Wiering, Annette Aigner, Marieke van Rosmalen, Brigitta Globke, Brigitta Globke, Tomasz Dziodzio, Nathanael Raschzok, Nathanael Raschzok, Münevver Demir, Wenzel Schöning, Frank Tacke, Petra Reinke, Johann Pratschke, Robert Öllinger, Paul V. Ritschl, Paul V. Ritschl   +16 more
doaj   +1 more source

Doublesex mediates the development of sex-specific pheromone organs in Bicyclus butterflies via multiple mechanisms [PDF]

, 2019
Anupama Prakash, Antónia Monteiro
openalex   +1 more source

Canal of Nuck hernia containing the internal reproductive organs of both gender in a neonate with disorder of sex development: a rare case presentation

, 2023
Kamal H. Attia, Mehad H. Felemban, Ahmad Amer Al Boukai, Latifah A. Alfahad   +3 more
openalex   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source