Results 171 to 180 of about 3,431,915 (390)

Influence of Month of Birth on the Serum Hormone Concentrations and Weights of the Accessory Sex Organs and Testes during Maturation of the Male Laboratory Rat1 [PDF]

, 1980
E. J. MOCK, Arthur I. Frankel
openalex   +1 more source

Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress‐Related Male Reproductive Dysfunction

Advanced Science, EarlyView.
Psychological stress activates the sympathetic–adrenal axis, elevating norepinephrine (NE) and suppressing reproductive hormones, thereby impairing male reproduction. Excess NE overactivates and desensitizes β‐adrenergic receptors (β‐ARs), triggering Sertoli cell ferroptosis and disrupting spermatogenesis.
Lingyu Zhang, Shanfeng Gao, Xiaofan Xiong, Xin Liu, Rufeng Li, Xia Wang, Lin Han, Xuan Xiao, Xiaofei Wang, Wen Li, Yongxia Chang, Yuefeng Du, Juan Yang   +12 more
wiley   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Autoimmunity and organ damage in systemic lupus erythematosus

Nature Immunology, 2020
G. Tsokos
semanticscholar   +1 more source

Sex as a biological variable: Mechanistic insights and clinical relevance in solid organ transplantation [PDF]

, 2023
Yao Xiao, Andreas Schroeter, Friederike Martin, Tomohisa Matsunaga, Keita Nakamori, Maximilian J. Roesel, Marlena Habal, Anita S. Chong, Hao Zhou, Stefan G. Tullius   +9 more
openalex   +1 more source

Tie2‐Dependent Mechanisms Influence Leptomeningeal Collateral Dynamics and Reperfusion Following Stroke

Advanced Science, EarlyView.
This work demonstrates that endothelial EphA4 limits Tie2 activation and curbs leptomeningeal collateral expansion after ischemic stroke. Pharmacological activation of Tie2 by an Ang‐1 mimetic or genetic loss of EphA4 stimulates collateral vessel growth, improves cerebral perfusion, and enhances neurological recovery.
Alexandra M. Kaloss, Caroline de Jager, Kennedie Lyles, Nathalie A. Groot, Jackie Zhu, Yu Lin, Michael Chen, Hehuang Xie, John B. Matson, Michelle H. Theus   +9 more
wiley   +1 more source

A Review on the Sex Differences in Organ and System Pathology with Alcohol Drinking.

Current Drug Abuse Reviews, 2017
V. Vatsalya, H. Liaquat, Kuldeep Ghosh, S. Mokshagundam, C. McClain   +4 more
semanticscholar   +1 more source

An Analysis by the European Committee on Organ Transplantation of the Council of Europe Outlining the International Landscape of Donors and Recipients Sex in Solid Organ Transplantation [PDF]

, 2022
Emanuele Cozzi, Marina Álvarez Benito, Mar Carmona, Beatriz Mahíllo, John Forsythe, Mar Lomero, Marta López‐Fraga, Ruth Sapir‐Pichhadze, Massimo Cardillo, Beatriz Domínguez‐Gil   +9 more
openalex   +1 more source

Gut Microbial Genetic Variation Prolongs Host Healthy Longevity and Remodels Metabolome and Proteome in Drosophila Melanogaster

Advanced Science, EarlyView.
This study reveals that specific genetic variations in gut‐residing Saccharomyces cerevisiae significantly extend healthspan and lifespan in Drosophila melanogaster. These mutants rejuvenate aged intestinal metabolism, upregulate mitochondrial proteins, and enhance energy pathways.
Liying Wang, Ziling Yang, Yulu Pang, Xinyue Wu, Xinrong Zhang, Tao Zhu, Xiaoyue Ding, Wei Liu, Yuan Zhou, Pengcheng Zhang, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Sex differences in baroreflex sensitivity, heart rate variability, and end organ damage in the TGR(mRen2)27 rat

, 2011
Megan S. Johnson, Vincent G. DeMarco, Cheryl M. Heesch, Adam Whaley‐Connell, Rebecca I. Schneider, Nathan Rehmer, Roger D. Tilmon, Carlos M. Ferrario, James R. Sowers   +8 more
openalex   +2 more sources