Estrogen-related mechanisms in sex differences of hypertension and target organ damage
Hypertension (HTN) is a primary risk factor for cardiovascular (CV) events, target organ damage (TOD), premature death and disability worldwide. The pathophysiology of HTN is complex and influenced by many factors including biological sex.
Andrea Rodrigues Sabbatini+1 more
doaj +2 more sources
Synergistic disruption of external male sex organ development by a mixture of four antiandrogens [PDF]
Reproduced with permission from Environmental Health Perspectives.Background: By disrupting the action of androgens during gestation, certain chemicals present in food, consumer products, and the environment can induce irreversible demasculinization and ...
Andreas Kortenkamp+14 more
core +4 more sources
Direct evidence supporting Darwin's hypothesis of cross-pollination promoted by sex organ reciprocity. [PDF]
Summary The floral phenotype plays a main role in the attraction and fit of pollinators. Both perianth traits and the positioning of sex organs can be subjected to natural selection and determine nonrandom mating patterns in populations.
Simón-Porcar VI+3 more
europepmc +2 more sources
STIMULATION OF SEX ORGAN FORMATION IN PHYTOPHTHORA BY ANTAGONISTIC SPECIES OF TRICHODERMA [PDF]
SUMMARY Two methods are described for the induction of sex organ formation in heterothallic Phytophthora species in response to Trichoderma, a volatile method and a direct inoculation (‘contact’) method.
C. M. Brasier
openalex +2 more sources
Studies on sex-organ development. The hormonal regulation of steroidogenesis and adenosine 3′:5′-cyclic monophosphate in embryonic-chick ovary [PDF]
1. We investigated the production of steroid hormones by the ovaries of the developing embryonic chick under conditions of organ culture. Radioimmunoassay techniques were used to measure the amount of steroid hormone released into the culture medium ...
Christina T. Teng, C S Teng
openalex +2 more sources
Studies on sex-organ development. Ontogeny of cytoplasmic oestrogen receptor in chick Müllerian duct [PDF]
Oestradiol receptors were observed in the cytoplasm of the chick Müllerian duct at several embryonic stages. The sedimentation coefficients and the dissociation constants of the receptor protein remained unchanged throughout the various stages of ...
C S Teng, Christina T. Teng
openalex +2 more sources
Sex-biased gene expression across mammalian organ development and evolution
Sexually dimorphic traits are common among mammals and are specified during development through the deployment of sex-specific genetic programs. Because little is known about these programs, we investigated them using a resource of gene expression ...
Leticia Rodríguez-Montes+7 more
openalex +3 more sources
Selective estrogen receptor α activation disrupts sex organ differentiation and induces expression of vitellogenin II and very low-density apolipoprotein II in Japanese quail embryos [PDF]
The Japanese quail (Coturnix japonica) is a widely used model species for studying the roles of steroid hormones in avian sex differentiation. The aim of the present study was to elucidate the significance of estrogen receptors alpha and beta (ERalpha ...
Anna Mattsson+2 more
openalex +2 more sources
Organ Weights in Relation to Age and Sex in Cynomolgus Monkeys (Macaca fascicularis)
Laboratory animal research is an important contributor to both human and animal medicine. Currently, there is extensive use of cynomolgus monkeys (Macaca fascicularis) in pathology and toxicology research.
Rachel Amato+3 more
semanticscholar +1 more source
ObjectiveTo investigate the anti-carcinogenic effect of metronomic Celecoxib (i.e., frequent administration in clinically available doses) against hepatocellular carcinoma (HCC) in the perspective of metastasis, spontaneous hepatocarcinogenesis, cancer ...
Chun-Chieh Yeh+15 more
doaj +1 more source