Barriers and Opportunities to Increase Utilization of Donor Kidneys After Death Determined by Circulatory Criteria Among Children and Adults: A Narrative Review. [PDF]
Robinson C +5 more
europepmc +1 more source
Four distinct satellite glial cell subtypes are identified in mouse dorsal root ganglia using single‐cell RNA sequencing and spatial validation. These subtypes show unique marker profiles and anatomical distributions. Human dorsal root ganglia display layered perisomatic organization with differential marker expression.
Ole Andreas Ahlgreen +13 more
wiley +1 more source
This study identifies the transcription factor ETV1 as a key driver of CD4⁺ T cell‐mediated intestinal inflammation in inflammatory bowel disease (IBD). ETV1 promotes CD4⁺ T cell activation, proliferation, and Th17 differentiation by activating the amino acid transporter SLC7A5, fueling metabolic reprogramming.
Yan Shi +8 more
wiley +1 more source
Sex-related differences in antimicrobial dosing for sepsis: Bridging the equity gap. [PDF]
Barrasa H, Balziskueta G, Rello J.
europepmc +1 more source
ITM2B Truncation Promotes Migrasome Formation to Accelerate Renal Cell Carcinoma Growth
This study identifies truncated ITM2B as a regulator of migrasome formation in renal cell carcinoma (RCC) cells. The ITM2B truncation not only facilitates migrasome formation by recruiting TSPAN4, but also sorts active caspase‐7 into migrasomes. The internalization of active caspase‐7‐enriched migrasomes by macrophages stimulates IL‐6 secretion to ...
Qi‐tao Chen +10 more
wiley +1 more source
Association between serum phosphate levels and 28-day mortality in patients with sepsis-associated liver injury: a cohort study. [PDF]
Ao T, Huang Y, Zhen P, Hu M.
europepmc +1 more source
Bats, Bacteria, and Bat Smell V.2.0: Repeatable Sex-Specific Differences in Scent Organ Microbiota [PDF]
Öncü Maracı +6 more
openalex +1 more source
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu +15 more
wiley +1 more source
Association between emergency department-to-intensive care unit transfer time and mortality in patients with septic shock: a target trial emulation with septic shock in South Korea. [PDF]
Cha JH +9 more
europepmc +1 more source

