Sex Steroids and the Organization of the Human Brain [PDF]
The Journal of Neuroscience, 2012 Studying the biological mechanisms underlying sexual differentiation in the human brain provides important insights into the etiology and trajectory of neurodevelopmental disorders in males and females ([Baron-Cohen et al., 2011][1]). Sex steroid hormones, the end products of the hypothalamus-
P. Cédric M. P. Koolschijn +1 more
openaire +3 more sources
Sex hormone-binding globulin regulation of androgen bioactivity in vivo : validation of the free hormone hypothesis [PDF]
, 2016 Sex hormone-binding globulin (SHBG) is the high-affinity binding protein for androgens and estrogens. According to the free hormone hypothesis, SHBG modulates the bioactivity of sex steroids by limiting their diffusion into target tissues.
Antonio, Leen +15 more
core +2 more sources
Synergistic disruption of external male sex organ development by a mixture of four antiandrogens [PDF]
, 2009 Reproduced with permission from Environmental Health Perspectives.Background: By disrupting the action of androgens during gestation, certain chemicals present in food, consumer products, and the environment can induce irreversible demasculinization and ...
Andreas Kortenkamp +14 more
core +3 more sources
Frontiers in Physics, 2023 Introduction: Current small-animal PET instrumentation provides sufficient resolution, sensitivity, and quantitative accurate information on the radiotracer distribution within the whole body.
Thomas Wanek +12 more
doaj +1 more source
Embracing Sex-specific Differences in Engineered Kidney Models for Enhanced Biological Understanding [PDF]
, 2023 In vitro models play a crucial role in advancing our understanding of biological processes, disease mechanisms, and developing screening platforms for drug discovery. Kidneys play an instrumental role in transport and elimination of drugs and toxins.
arxiv +1 more source
Estrogen-related mechanisms in sex differences of hypertension and target organ damage
Biology of Sex Differences, 2020 Hypertension (HTN) is a primary risk factor for cardiovascular (CV) events, target organ damage (TOD), premature death and disability worldwide. The pathophysiology of HTN is complex and influenced by many factors including biological sex.
Andrea Rodrigues Sabbatini +1 more
doaj +1 more source
Cell Transplantation, 2017 Background: After living donor liver transplantation (LDLT), rising serum bilirubin levels commonly indicate insufficient numbers of hepatocytes are available to metabolize bilirubin into biliverdin. Recovery of bilirubin levels is an important marker of
Ta-Lun Kao +7 more
doaj +1 more source
Effect of heat stress on sex hormones, sex organ weight and relationships with sexual puberty in male rats [PDF]
Iraqi Journal of Veterinary Sciences, 2019 This study was designed to investigate the effect of chronic and acute heat stress on sex hormones level and their relationship to sexual puberty in male rats.
hiyam matty, Ashwaq Hassan
doaj +1 more source
Synergy from reproductive division of labor and genetic complexity drive the evolution of sex [PDF]
J Biol Phys (2018). https://doi.org/10.1007/s10867-018-9485-8, 2017 Computer experiments that mirror the evolutionary dynamics of sexual and asexual organisms as they occur in nature, tested features proposed to explain the evolution of sexual recombination. Results show that this evolution is better described as a network of interactions between possible sexual forms, including diploidy, thelytoky, facultative sex ...
arxiv +1 more source
Evolution of plant reproduction: from fusion and dispersal to interaction and communication [PDF]
, 2009 Based on the existing data concerning the evolution of the sexual reproduction, it is argued that the processes of sex differentiation and interactions play a key role in evolution. From the beginning environment and organism are unified.
Willemse, M.T.M.
core +1 more source