Sex hormone-binding globulin regulation of androgen bioactivity in vivo : validation of the free hormone hypothesis [PDF]
Sex hormone-binding globulin (SHBG) is the high-affinity binding protein for androgens and estrogens. According to the free hormone hypothesis, SHBG modulates the bioactivity of sex steroids by limiting their diffusion into target tissues.
Antonio, Leen +15 more
core +2 more sources
Introduction: Current small-animal PET instrumentation provides sufficient resolution, sensitivity, and quantitative accurate information on the radiotracer distribution within the whole body.
Thomas Wanek +12 more
doaj +1 more source
PREMISE OF THE STUDY Populations of heterostylous species are characterized by two or three floral morphs with reciprocal positioning of stigmas and anthers.
V. Ferrero +4 more
semanticscholar +1 more source
Evolution of plant reproduction: from fusion and dispersal to interaction and communication [PDF]
Based on the existing data concerning the evolution of the sexual reproduction, it is argued that the processes of sex differentiation and interactions play a key role in evolution. From the beginning environment and organism are unified.
Willemse, M.T.M.
core +1 more source
Critical care provision after colorectal cancer surgery [PDF]
Background: Colorectal cancer (CRC) is the 2nd largest cause of cancer related mortality in the UK with 40 000 new patients being diagnosed each year. Complications of CRC surgery can occur in the perioperative period that leads to the requirement of ...
Dale, C.D. +6 more
core +1 more source
Androgen conspires with the CD8+ T cell exhaustion program and contributes to sex bias in cancer
Sex bias exists in the development and progression of nonreproductive organ cancers, but the underlying mechanisms are enigmatic. Studies so far have focused largely on sexual dimorphisms in cancer biology and socioeconomic factors.
H. Kwon +20 more
semanticscholar +1 more source
BackgroundThe incidence rate of lung large cell neuroendocrine carcinoma (LCNEC) in lung cancer is low, but the malignancy is high and the prognosis is poor.
Chang-fu Liu, Yu-jian Tao
doaj +1 more source
Assay for free secretory component and methods for monitoring organ rejection [PDF]
Methods of monitoring and detecting the early onset of organ injury incident rejection of a organ rejection in an animal are disclosed. The described methods are capable of distinguishing organ rejection injury from other organ tissue damage in the ...
Goldblum, Randall M. +1 more
core +1 more source
Effect of heat stress on sex hormones, sex organ weight and relationships with sexual puberty in male rats [PDF]
This study was designed to investigate the effect of chronic and acute heat stress on sex hormones level and their relationship to sexual puberty in male rats.
hiyam matty, Ashwaq Hassan
doaj +1 more source
Screening of endocrine organ-specific humoral autoimmunity in 47,XXY Klinefelter's syndrome reveals a significant increase in diabetes-specific immunoreactivity in comparison with healthy control men. [PDF]
The aim of this study was to evaluate the frequency of humoral endocrine organ-specific autoimmunity in 47,XXY Klinefelter’s syndrome (KS) by investigating the autoantibody profile specific to type 1 diabetes (T1DM), Addison’s disease (AD), Hashimoto ...
ANZUINI, Antonella +7 more
core +1 more source

