Results 71 to 80 of about 3,431,915 (390)

Differential gene expression among three sex types reveals a MALE STERILITY 1 (CpMS1) for sex differentiation in papaya

BMC Plant Biology, 2019
Background Carica papaya is a trioecious plant species with a genetic sex-determination system defined by sex chromosomes. Under unfavorable environmental conditions male and hermaphrodite exhibit sex-reversal.
Dessireé Zerpa-Catanho, Jennifer Wai, Ming Li Wang, Li’ang Yu, Julie Nguyen, Ray Ming   +5 more
doaj   +1 more source

Presumed post-mortem donors: the degree of information among university students

BMC Medical Ethics, 2021
Background Organ transplantation represents the most effective and acceptable therapy for end-stage organ failure. However, its frequent practice often leads to a shortage of organs worldwide. To solve this dilemma, some countries, such as Portugal, have
Rita da Silva Clemente Pinho, Cristina Maria Nogueira da Costa Santos, Ivone Maria Resende Figueiredo Duarte   +2 more
doaj   +1 more source

The Effects of Biological Sex on Sepsis Treatments in Animal Models: A Systematic Review and a Narrative Elaboration on Sex- and Gender-Dependent Differences in Sepsis

Critical Care Explorations, 2021
OBJECTIVES:. Preclinical studies provide an opportunity to evaluate the relationship between sex and sepsis, and investigate underlying mechanisms in a controlled experimental environment.
MengQi Zhang, BSc, Joshua Montroy, MSc, Rahul Sharma, HBSc, Dean A. Fergusson, MHA, PhD, Asher A. Mendelson, MD, PhD, FRCPC, Kimberly F. Macala, MD, FRCPC, Stephane L. Bourque, PhD, Jared M. Schlechte, BSc, Mikaela K. Eng, MSc, Braedon McDonald, MD, PhD, FRCPC, Sean E. Gill, PhD, Kirsten M. Fiest, PhD, Patricia C. Liaw, MSc, PhD, Alison Fox-Robichaud, MSc, MD, FRCPC, Manoj M. Lalu, MD, PhD, FRCPC, on behalf of the Canadian Critical Care Translational Biology Group and the Sepsis Canada National Preclinical Sepsis Platform   +15 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Increased Risk of Cutaneous Squamous Cell Carcinoma in Organ Transplant Recipients and Patients on Chronic Dialysis: A Cancer Registry-based Study in Taiwan

Acta Dermato-Venereologica, 2019
This study investigated the predominant skin cancer subtype among organ transplant recipients, patients on chronic dialysis, and patients with chronic kidney disease in Asian subjects. Among 23,644 patients with skin cancer, identified from Taiwan Cancer
Chao-Hsiun Tang, Yuh-Mou Sue, Wen-Ting Hsieh, Ya-Hui Wang, Chia-Chen Wang   +4 more
doaj   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

Patterns of the electric organ discharge during courtship and spawning in the mormyrid fish, Pollimyrus isidori [PDF]

, 1989
Pollimyrus isidori's electric organ discharge (EOD) is of the pulse type. Patterns of EOD intervals were investigated prior to, during and following spawning behaviors as related with overt behaviors, and with the sound production by the nestbuilding ...
Bratton, Bradford O., Kramer, Bernd
core   +1 more source

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

Sex and gender considerations in transplantation research: protocol for a scoping review

Systematic Reviews, 2017
Background Despite the growing appreciation of the importance of sex and gender considerations in transplantation research, there is currently no framework or good practice guidelines for the appropriate handling of sex and gender issues in human ...
Claudie Laprise, Vikas Srinivasan Sridhar, Lori West, Bethany Foster, Louise Pilote, Ruth Sapir-Pichhadze   +5 more
doaj   +1 more source

Outcomes following oesophagectomy in patients with oesophageal cancer: a secondary analysis of the ICNARC Case Mix Programme Database [PDF]

, 2009
Introduction: This report describes the case mix and outcomes of patients with oesophageal cancer admitted to adult critical care units following elective oesophageal surgery in England, Wales and Northern Ireland.
Alderson, Derek, Cromwell, David A., Harrison, D. A. (David A.), Palser, Thomas R., Park, Daniel P., Perkins, Gavin D., Rowan, Katherine M., Smith, F. Gao (Fang Gao), Welch, Catherine A.   +8 more
core   +4 more sources