Results 51 to 60 of about 1,336,652 (309)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A sex ratio is one of the most basic demographic estimates produced because it is easy to collect and provides deeper insight into population dynamics for the species under consideration.
J. E. Kahn +4 more
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Patterns of silver eel (Anguilla anguilla L.) sex ratio in a catchment [PDF]
Changes in the numbers and size-class structure of European silver eels, Anguilla anguilla, in the River Fre´mur (France) were examined over a 9-year period after installation of downstream eel passes.
Guillouët, Jérôme +9 more
core +1 more source
Background The Y-chromosomal diversity in the African buffalo (Syncerus caffer) population of Kruger National Park (KNP) is characterized by rainfall-driven haplotype frequency shifts between year cohorts.
Greyling Barend J +7 more
doaj +1 more source
Using precise genetic models, the evolution of the sex ratio in a population in which interactions between siblings exist but these interactions are not symmetrical with respect to the sexes has been studied. Some interesting differences between co-operative and aggressive models have emerged. © 1982.
openaire +4 more sources
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Trends and seasonal variations in human secondary sex ratio in Southwest Nigeria: A 10-year survey
Introduction: Secondary sex ratio is the number of live male births per 100 female births. In humans, the primary sex ratio, which is the sex ratio at conception, is expected to be 1:1 in natural populations based on the law of independent assortment of ...
Samson Taiwo Fakorede +5 more
doaj +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source

