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Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency
Advanced Science, EarlyView.How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen +10 more
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Amphibian sex determination and sex reversal
Cellular and Molecular Life Sciences, 1999Amphibians employ a genetic mechanism of sex determination, according to all available information on sex chromosomes or breeding tests. Sex reversal allows breeding tests to establish which sex is heterogametic and provides an indication of the mechanism of sex determination. Cases of spontaneous and experimental sex reversal (by temperature, hormones
B M N Wallace
exaly +3 more sources
Sex determination and sex reversal
Current Opinion in Genetics & Development, 2006Sex determination in mammals is based on a genetic cascade that controls the fate of the gonads. Gonads will then direct the establishment of phenotypic sex through the production of hormones. Different types of sex reversal are expected to occur if mutations disrupt one of the three steps of gonadal differentiation: formation of the gonadal primordia,
G. Camerino +3 more
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Sexual Development, 2016
Sexual differentiation in birds is controlled genetically as in mammals, although the sex chromosomes are different. Males have a ZZ sex chromosome constitution, while females are ZW. Gene(s) on the sex chromosomes must initiate gonadal sex differentiation during embryonic life, inducing paired testes in ZZ individuals and unilateral ovaries in ZW ...
Andrew T, Major, Craig A, Smith
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Sexual differentiation in birds is controlled genetically as in mammals, although the sex chromosomes are different. Males have a ZZ sex chromosome constitution, while females are ZW. Gene(s) on the sex chromosomes must initiate gonadal sex differentiation during embryonic life, inducing paired testes in ZZ individuals and unilateral ovaries in ZW ...
Andrew T, Major, Craig A, Smith
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Group sex ratio and sex reversal
Journal of Theoretical Biology, 1980Abstract In hermaphroditic fishes, the initiation of sex reversal by male removal explains the replacement of lost males but does not explain how the number of males in a group may increase. Since numerous species apparently cannot produce primary males, a second means of initiating sex reversal must exist.
Douglas Y. Shapiro, Roger Lubbock
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1983
In most mammals, XX and XO individuals develop as phenotypic females, XY and XXY individuals as males. However, in mice as in other mammals [2], a number of abnormal genetic situations are known in which phenotypic sex and chromosomal sex are not concordant; these are often associated with various types of intersexual development.
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In most mammals, XX and XO individuals develop as phenotypic females, XY and XXY individuals as males. However, in mice as in other mammals [2], a number of abnormal genetic situations are known in which phenotypic sex and chromosomal sex are not concordant; these are often associated with various types of intersexual development.
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Xp duplications and sex reversal
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1995Abstract Male to female sex reversal has been observed in individuals with duplications of the short arm of the X chromosome. The study of Xp duplicated patients demonstrated that sex reversal results from the presence of two active copies of the DSS (dosage sensitive sex reversal) locus.
E, Zanaria +6 more
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Sex reversal and aromatase in chicken
Journal of Experimental Zoology, 2001AbstractAromatase inhibitors administered before sexual differentiation of the gonads can induce sex reversal in female chickens. To analyze the process of sex reversal, we have followed for several months the changes induced by Fadrozole, a nonsteroidal aromatase inhibitor, in gonadal aromatase activity and in morphology and structure of the female ...
S, Vaillant +3 more
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Journal of the American Veterinary Medical Association, 1994
A 5-month-old llama was examined for evaluation of sexually ambiguous external genitalia. To determine the phenotypic, chromosomal, and gonadal sex of the llama, transrectal palpation and ultrasonography, contrast cystography, karyotype evaluation, laparoscopy, and necropsy were performed. A karyotype of 74,XX and finding of components of the müllerian
C E, Wilker +5 more
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A 5-month-old llama was examined for evaluation of sexually ambiguous external genitalia. To determine the phenotypic, chromosomal, and gonadal sex of the llama, transrectal palpation and ultrasonography, contrast cystography, karyotype evaluation, laparoscopy, and necropsy were performed. A karyotype of 74,XX and finding of components of the müllerian
C E, Wilker +5 more
openaire +2 more sources