Results 81 to 90 of about 15,924,749 (378)
Sex ratio theory in geographically structured populations [PDF]
Heredity, 1986 Equilibrium sex ratios have been determined analytically under Wright's island model in order to determine the effect of population structure with limited dispersal. When mating occurs before dispersal, the dispersal rate has little or no effect, and the equilibrium sex ratio remains the same as under complete dispersal (the standard model of local ...
openaire +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Sex-linked genes in age-structured populations [PDF]
Heredity, 1978 We study the progress towards equilibrium of the frequencies of sex-linked genes in elementary discrete time models of age-structured, overlapping generation populations. It is found that, if a finite upper age limit is assumed, the difference in the frequencies of an allele in males and females will oscillate as in the familiar non-overlapping ...
openaire +2 more sources
What Is Safe Sex ? Understanding the Need for Sex Education Reform
, 2020 Currently, the United States has no standardized requirement for sex education. This has precipitated a large gap in knowledge about safe sex and a lack of consensus in current social and educational policy.
Baker, Julianne
core
An Experimental Test of Buffer Utility as a Technique for Managing Pool-Breeding Amphibians [PDF]
, 2015 Vegetated buffers are used extensively to manage wetland-dependent wildlife. Despite widespread application, buffer utility has not been experimentally validated for most species.
Babbitt, Kimberly J. +1 more
core +4 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Life Satisfaction: Measurement Invariance and Correlations with Adolescent Adjustment [PDF]
, 2020 Background Low life satisfaction during adolescence has been associated with adjustment problems. There are few well-validated measures available to assess adolescents’ life-satisfaction.
Farrell, Albert D. +2 more
core +1 more source
Family structure and breakfast consumption of 11-15 year old boys and girls in Scotland, 1994-2010 [PDF]
, 2012 Background The benefits of breakfast during childhood and adolescence have been reported previously though few studies have considered family structure inequalities in breakfast consumption. The proportion of young people living in non-traditional family
Currie, Candace +2 more
core +5 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Sex and gender differences in substance use disorders.
Clinical Psychology Review, 2017 The gender gap in substance use disorders (SUDs), characterized by greater prevalence in men, is narrowing, highlighting the importance of understanding sex and gender differences in SUD etiology and maintenance.
R. K. McHugh +3 more
semanticscholar +1 more source