Results 61 to 70 of about 1,617,182 (292)

The recovery experience of people who were sex trafficked: the thwarted journey towards goal pursuit

open access: yesBMC International Health and Human Rights, 2019
Background In 2010, a shelter programme was established in the Netherlands to provide social and health services for trafficked people. This article describes how service users in this programme conceptualized and experienced their own process of ...
Roderik F. Viergever   +4 more
doaj   +1 more source

Sex Work, Migration, and Human Trafficking in South Africa: From polarised arguments to potential partnerships [PDF]

open access: yes, 2019
In South Africa, the conflation of sex work with human trafficking means that migrant/mobile sex workers are often framed as victims of trafficking while arguments for the decriminalisation of sex work are discounted due to claims about the risks of ...
Ntokozo Yingwana   +5 more
core   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li   +15 more
wiley   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

open access: yesAdvanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj   +25 more
wiley   +1 more source

Sex trafficking of girls and women : Evidence from Anantapur district, Andhra Pradesh [PDF]

open access: yes
A crucial gap in the trafficking literature from India is the dearth of primary data and micro studies that could be used for vulnerability mapping of the source areas and addressing the identified risk factors.
U. Vindhya, V. Swathi Dev
core  

Disjointed Service: An English Case Study of Multi-Agency Provision in Tackling Child Trafficking [PDF]

open access: yes, 2015
This paper examines the issue of child trafficking in the United Kingdom and of multi-agency responses in tackling it. The UK, as a signatory to the recent trafficking protocols, is required to implement measures to identify and support potential ...
Zeibeda Sattar   +5 more
core   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

Trafficking experiences and psychological dysfunction among female trafficking survivors returning to Vietnam

open access: yesThe Lancet Global Health, 2014
Background: Studies have shown high levels of depression and post-traumatic stress disorder in female trafficking survivors and that mental disorders might be associated with factors such as pretrafficking childhood abuse, trafficking trauma, and unmet ...
PhuongThao D Le, MPH
doaj   +1 more source

Other title: Human trafficking

open access: yes, 2016
Palm card.; "Mike DeWine, Ohio Attorney General."; "Created: 7/20/2016 ..."--Document properties screen.; "Protecting Ohio's Families."On verso: Recognizing the problem: Sex trafficking ; Labor trafficking ; Report suspicious ...

core  

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han   +24 more
wiley   +1 more source

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