Alimentary Pharmacology &Therapeutics, EarlyView.Alpha‐1 antitrypsin deficiency is a genetic disease that affects the lungs and the liver. The role of the heterozygous genetic defect in the development of liver cancer in patients with cirrhosis is unclear. Our study found that carrying the Pi*MZ genotype increases the risk of developing liver cancer.
Lorenz Balcar +18 more
wiley +1 more source
Bridging Gaps in Adolescent and Adult Sexual Health: Training Medical Students as Educators. [PDF]
CureusAbraham AS +6 more
europepmc +1 more source
British Journal of Pharmacology, EarlyView.Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller +3 more
wiley +1 more source
Developing and testing a digital harm reduction app for GBMSM engaging in chemsex: a feasibility study grounded in users' lived experiences. [PDF]
Harm Reduct JStrong C +8 more
europepmc +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
Evaluating treatment outcomes across four substance use treatment settings: a 12-month longitudinal study in Iran. [PDF]
Harm Reduct JMirzaei S +4 more
europepmc +1 more source
U.S. International AIDS Programs: A New Model of Humanitarian Initiatives? [PDF]
, 2006 Dietrich, John W.
core +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Alarming trends show that vaping e‐cigarettes containing synthetic cannabinoid receptor agonists, such as JWH‐018, is increasing among youth. However, the effects of these trends are unclear in both sexes. We therefore characterized the neuropharmacological effects of adolescent JWH‐018 inhalation in male and female rats.
Nicholas Pintori +7 more
wiley +1 more source
Influence of education status, age, and gender on HIV prevention awareness and preferences among youth in a rural Ugandan district: a cross-sectional study. [PDF]
BMC Public HealthSsali PW +9 more
europepmc +1 more source
Maternal anorexia nervosa and risk of mental and neurodevelopmental morbidity in offspring
Child and Adolescent Mental Health, EarlyView.Background Anorexia nervosa has the potential to affect fetal neurodevelopment. We examined the association between maternal anorexia nervosa and mental, substance‐related, and neurodevelopmental morbidity in offspring. Methods We conducted a retrospective cohort study of 1,269,370 children in Quebec, Canada, between 2006 and 2022.
Sam Amar +8 more
wiley +1 more source