Results 251 to 260 of about 2,093,356 (349)

Effects of fenfluramine and sigma‐1‐dependent pharmacological and genetic modulation in a mouse kindling model

open access: yesEpilepsia, EarlyView.
Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden   +5 more
wiley   +1 more source

Pinta tu Raya ASI [Set your Limit LIKE THIS]: an educational intervention using immersive reality to prevent Child Sexual Abuse in Mexico. [PDF]

open access: yesFront Public Health
Rivera-Rivera L   +6 more
europepmc   +1 more source

Febrile status epilepticus and epileptogenesis: The FEBSTAT study

open access: yesEpilepsia Open, EarlyView.
Abstract The multicenter FEBSTAT study (Consequences of Prolonged Febrile Seizures in Childhood: https://grantome.com/grant/NIH/R37‐NS043209‐12; PI S. Shinnar) examined the outcome of febrile status epilepticus (FSE) in over 200 prospectively enrolled infants, with many followed for 10 years after FSE.
Darrell V. Lewis   +14 more
wiley   +1 more source

A digital intervention to improve mental health and interpersonal resilience in young people who have experienced technology-assisted sexual abuse: a feasibility clinical trial. [PDF]

open access: yesChild Adolesc Ment Health
Bucci S   +20 more
europepmc   +1 more source

Status epilepticus: Updates on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Discriminating childhood traumatic experiences by molecular profiles: the case of neglect and sexual abuse. [PDF]

open access: yesEur J Psychotraumatol
Pesca C   +5 more
europepmc   +1 more source

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