Results 71 to 80 of about 1,050,527 (294)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Internet addiction and loneliness among children and adolescents in the education setting: an empirical pilot study [PDF]

open access: yes, 2014
Research into various behavioural addictions has shown that such behaviour can negatively impact psychological wellbeing. One behavioural addiction that has been increasingly studied empirically is that of Internet Addiction (IA).
Griffiths, M.D.   +5 more
core  

Sexual Dysfunction and Sexual Behaviors in a Sample of Brazilian Male Substance Misusers

open access: yesAmerican Journal of Men's Health, 2016
The aim of this study was to evaluate the potential relationship between self-reported sexual dysfunction, sexual behavior, and severity of addiction of drug users.
Alessandra Diehl MSc   +4 more
doaj   +1 more source

Online erotica usage as a mediator between internet addiction and engagement in risky online sexual behaviors

open access: yesCyberpsychology: Journal of Psychosocial Research on Cyberpspace, 2016
In this study, we examined the links between Internet addiction, engagement in online erotica (including pornography usage and usage of sex-based Internet chat sites), and engagement in risky online sexual behaviors, in this case, sending sexually ...
Michelle Drouin, Daniel A. Miller
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Triage & medical guidelines for sexual assault evaluation [PDF]

open access: yes, 2012
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from pdf caption (viewed on August 19, 2015).The ...

core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Structural equation modeling of the relationship between childhood trauma and sexual addiction with the mediating role of perceived social support, mentalization and attachment styles [PDF]

open access: yesمجله علوم روانشناختی
Background: Children facing challenges such as social deficiencies during childhood may struggle in social interactions and unhealthy emotional relationships, thus increasing their vulnerability to sexual addiction.
mona Adibifar   +3 more
doaj  

Response of clomipramine in sexual addiction

open access: yesEuropean Psychiatry, 1995
SummaryTwo cases of sexual addiction for more than five years treated with psychological treatment and clomipramine showed marked improvement after six to nine months. It is postulated that these disorders could be variants of obsessive compulsive disorder.
M, Azhar, S, Varma
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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