Results 71 to 80 of about 184,904 (290)

Transactional sex and intersecting vulnerabilities: a multicountry cross-sectional study of pregnant and parenting adolescents in sub-Saharan Africa

BMJ Public Health
Introduction Transactional sex among adolescents in sub-Saharan Africa is well documented, with extensive scholarship describing its meanings, drivers and implications.
Anthony Idowu Ajayi, Caroline Kabiru, Beryl Nyatuga Machoka, Jalisa Stanislaus, Catherine Asego   +4 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Determinants of access to HIV testing and counselling services among female sex workers in sub-Saharan Africa: a systematic review

BMC Public Health, 2019
Background HIV testing and counselling (HTC) is an essential component for HIV prevention and a critical entry point into the HIV continuum of care and treatment.
Soori Nnko, Evodius Kuringe, Daniel Nyato, Mary Drake, Caterina Casalini, Amani Shao, Albert Komba, Stefan Baral, Mwita Wambura, John Changalucha   +9 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

The dynamics of family planning and abortion services during COVID-19: perspectives from healthcare providers and clients in Burkina Faso

Reproductive Health
Background The novel SARS-CoV-2 (COVID-19) led to an unprecedented increase in demand on health systems to care for people infected, necessitating the allocation of significant resources, especially medical resources, towards the response.
Eunice Nahyuha Chomi, Marie Gisèle Donessouné, Armel Sogo, Armando Humberto Seuc, Gabriela Garcia Camacho, Ali Moazzam, Seni Kouanda, the WHO HRP Social Science Research Team   +7 more
doaj   +1 more source

Silenced, stigmatised and struggling: early childbearing, minority stress and mental distress among pregnant and parenting adolescent girls in an urban informal settlement in Kenya – an explanatory qualitative study

BMJ Public Health
Background Early pregnancy is associated with poor mental health outcomes, but little is known about the extent to which stressors contribute to mental health challenges among pregnant or parenting adolescents. Informed by Meyer’s minority stress theory,
Anthony Idowu Ajayi, Caroline Kabiru, Sally Atieno Odunga, Beryl Nyatuga Machoka, Vallery Auma Obure   +4 more
doaj   +1 more source

Repoliticising sexual and reproductive health and rights [PDF]

Reproductive Health Matters, 2011
This editorial explores what is happening globally towards achieving sexual and reproductive health and rights. It discusses the perceived fragmentation of work in this field and the de-politicization of the process and the goals involved as the number of issues groups and networks involved has burgeoned.
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Assessment of Health Facility Compliance with Standards and Perception of Adolescents to Quality of Sexual and Reproductive Health Services in Kilindi, Tanga Tanzania [PDF]

, 2012
Promoting healthy practices during adolescence and taking steps for better protection of young people from health risks is critical to the future of countries‘ health.
Maro, G, Maro, Godson
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source