Results 51 to 60 of about 181,910 (349)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Knowledge of the abortion law and key legal issues of sexual and reproductive health and rights among recently arrived migrants in Sweden: a cross-sectional survey

BMC Public Health, 2023
Background Sexual and reproductive health and rights (SRHR), including access and information on the laws and policies related to abortion, varies considerably between countries.
Veronika Tirado, Anna Mia Ekström, Nicola Orsini, Claudia Hanson, Susanne Strömdahl   +4 more
doaj   +1 more source

Fulfillment of Maternal Health As Part of Human Rights: A Case Study of Banyuwangi Municipality of East Java, Indonesia [PDF]

, 2011
This article is result of research on the fulfillment of maternal health which conducted in one of city in East Java Indonesia. Approach used for this research is human rights based which also utilise 3-A and 1-Q elements (availability, accessibility ...
Christanti, Inge, Herawati, Aloysia Vira, Simanjuntak, Yoan Nursari   +2 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Sexual rights and sexual pleasure: Sustainable Development Goals and the omitted dimensions of the leave no one behind sexual health agenda

Global Public Health, 2023
This commentary explores the missing discourse of sexual rights and sexual pleasure in the Sustainable Development Goals (SDG) that purport to leave no one behind.
Carmen H. Logie
doaj   +1 more source

Re-Costing Cairo: Revised Estimate of the Resource Requirements to Achieve the ICPD Goals [PDF]

, 2009
Achieving universal access to reproductive health, including family planning services and supplies, is essential to ensuring the health and well-being of women and their families.
Suzanna Dennis
core  

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Young people with disabilities and their sexual health: a descriptive review of needs, recommendations and interventions

BMC Public Health
Background Worldwide, almost 180 million young people aged between 10 and 24 live with disability. They are often perceived as asexual, lacking in sexual desires, or as sexually inadequate. The sexual health of young people with disabilities thus remains
Noëline Vivet, Elise de La Rochebrochard, Philippe Martin   +2 more
doaj   +1 more source

Sexual and Reproductive Health and Rights of Refugee Women in Europe: rights, policies, status and needs. Literature review [PDF]

, 2005
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Bosmans, Marleen, Janssens, Kristin, Temmerman, Marleen   +2 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source