Results 71 to 80 of about 181,910 (349)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

Adolescents Under International Law: Autonomy as the Key to Reproductive Health

, 2008
As a matter of policy, the reproductive and sexual health of adolescents matter because they comprise almost one half of the world\u27s population. As a matter of international human rights law, adolescents have reproductive and sexual health rights ...
Haider, Aliya
core  

[Introduction] Re-situating abortion: bio-politics, global health and rights in neo-liberal times [PDF]

, 2018
New modes of neoliberal and rights-based reproductive governance are emerging across the world which either paradoxically foreclose access to universal health services or promote legislative reform without providing a continuum of services on the ground.
de Zordo, Silvia, Unnithan, Maya
core   +2 more sources

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Mapping the evidence on interventions that mitigate the health, educational, social and economic impacts of child marriage and address the needs of child brides: a systematic scoping review

Sexual and Reproductive Health Matters
More than 650 million women alive today were married as children. Relative to efforts to prevent child marriage, efforts to support child brides have received much less attention.
Shatha Elnakib, Ahmed K. Ali, Kate Mieth, Venkatraman Chandra-Mouli   +3 more
doaj   +1 more source

Knowledge of reproductive and sexual rights among University students in Ethiopia: institution-based cross-sectional

BMC International Health and Human Rights, 2013
Background People have the right to make choices regarding their own sexuality, as far as they respect the rights of others. The knowledge of those rights is critical to youth’s ability to protect themselves from unwanted reproductive outcomes ...
Adinew Yohannes Mehretie, Worku Abebaw Gebeyehu, Mengesha Zelalem Birhanu   +2 more
doaj   +1 more source

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

Shaping the abortion policy – competing discourses on the Zambian termination of pregnancy act

International Journal for Equity in Health, 2019
Introduction The Zambian Termination of Pregnancy Act permits abortion on socio-economic grounds, but access to safe abortion services is limited and this constitutes a considerable problem for rights to sexual and reproductive health. The case of Zambia
Marte E. S. Haaland, Haldis Haukanes, Joseph Mumba Zulu, Karen Marie Moland, Charles Michelo, Margarate Nzala Munakampe, Astrid Blystad   +6 more
doaj   +1 more source

Working with boys and men for a change : lessons from Fiji : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Developmental Studies at Massey University, Palmerston North, New Zealand [PDF]

, 2005
Male involvement in sexual and reproductive health and anti-violence interventions are two of the more common entry points in working with men to achieve gender equality. The most promising interventions are those that challenge gender norms, questioning
Romanos, Annie
core